STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc22a25Solute carrier family 22 (Organic anion/cation transporter), member 9. (552 aa)    
Predicted Functional Partners:
Slc35f5
Solute carrier family 35, member F5 (Predicted).
    
 
 0.641
Slc7a12
Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 12.
   
 
 0.624
Slc22a18
Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney (By similarity). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
   
  
 0.588
Slc21a4
Solute carrier organic anion transporter family member 1A3; Mediates the Na(+)-independent transport of organic anions such as methotrexate, taurocholate, folate and prostaglandin E2. May contribute to renal secretion and/or reabsorption of hydrophobic anionic compounds. Mediates renal clearance of methotrexate from the blood; Belongs to the organo anion transporter (TC 2.A.60) family.
   
  
 0.581
Slc7a13
Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
   
 
 0.549
Slc35g3
Solute carrier family 35 member G3.
      
 0.535
RGD1565367
Similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2).
   
  
 0.531
Slco6b1
Solute carrier organic anion transporter family member.
   
  
 0.521
Glyatl2
Glycine N-acyltransferase-like protein Keg1; Acyltransferase which transfers the acyl group to the N- terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity).
   
  
 0.519
Slc4a1ap
Solute carrier family 4 member 1 adaptor protein.
      
 0.499
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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