node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccar2 | Edc4 | ENSRNOP00000024895 | ENSRNOP00000006345 | Cell cycle and apoptosis regulator 2. | Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). | 0.686 |
Ccar2 | Fbxo42 | ENSRNOP00000024895 | ENSRNOP00000068831 | Cell cycle and apoptosis regulator 2. | F-box protein 42. | 0.633 |
Ccar2 | Hao1 | ENSRNOP00000024895 | ENSRNOP00000006330 | Cell cycle and apoptosis regulator 2. | Hydroxyacid oxidase 1 (Mapped). | 0.578 |
Ccar2 | Kcnab2 | ENSRNOP00000024895 | ENSRNOP00000073699 | Cell cycle and apoptosis regulator 2. | Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Modulates the functional properties of KCNA4. Modulates the functional properties of KCNA5 (B [...] | 0.509 |
Ccar2 | Ranbp3 | ENSRNOP00000024895 | ENSRNOP00000067560 | Cell cycle and apoptosis regulator 2. | RAN-binding protein 3. | 0.826 |
Ccar2 | Rnf40 | ENSRNOP00000024895 | ENSRNOP00000025500 | Cell cycle and apoptosis regulator 2. | E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] | 0.568 |
Ccar2 | Sirt1 | ENSRNOP00000024895 | ENSRNOP00000070943 | Cell cycle and apoptosis regulator 2. | NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expres [...] | 0.832 |
Ccar2 | Snw1 | ENSRNOP00000024895 | ENSRNOP00000054619 | Cell cycle and apoptosis regulator 2. | Similar to Nuclear protein SkiP (Ski-interacting protein) (Predicted). | 0.525 |
Ccar2 | U2af2 | ENSRNOP00000024895 | ENSRNOP00000021392 | Cell cycle and apoptosis regulator 2. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.527 |
Ccar2 | Zfp326 | ENSRNOP00000024895 | ENSRNOP00000075187 | Cell cycle and apoptosis regulator 2. | Zinc finger protein 326; Belongs to the AKAP95 family. | 0.818 |
Edc4 | Ccar2 | ENSRNOP00000006345 | ENSRNOP00000024895 | Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). | Cell cycle and apoptosis regulator 2. | 0.686 |
Edc4 | Rnf40 | ENSRNOP00000006345 | ENSRNOP00000025500 | Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). | E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] | 0.643 |
Fbxo42 | Ccar2 | ENSRNOP00000068831 | ENSRNOP00000024895 | F-box protein 42. | Cell cycle and apoptosis regulator 2. | 0.633 |
Hao1 | Ccar2 | ENSRNOP00000006330 | ENSRNOP00000024895 | Hydroxyacid oxidase 1 (Mapped). | Cell cycle and apoptosis regulator 2. | 0.578 |
Hao1 | Kcnab2 | ENSRNOP00000006330 | ENSRNOP00000073699 | Hydroxyacid oxidase 1 (Mapped). | Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Modulates the functional properties of KCNA4. Modulates the functional properties of KCNA5 (B [...] | 0.638 |
Kcnab2 | Ccar2 | ENSRNOP00000073699 | ENSRNOP00000024895 | Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Modulates the functional properties of KCNA4. Modulates the functional properties of KCNA5 (B [...] | Cell cycle and apoptosis regulator 2. | 0.509 |
Kcnab2 | Hao1 | ENSRNOP00000073699 | ENSRNOP00000006330 | Voltage-gated potassium channel subunit beta-2; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Modulates the functional properties of KCNA4. Modulates the functional properties of KCNA5 (B [...] | Hydroxyacid oxidase 1 (Mapped). | 0.638 |
Ranbp3 | Ccar2 | ENSRNOP00000067560 | ENSRNOP00000024895 | RAN-binding protein 3. | Cell cycle and apoptosis regulator 2. | 0.826 |
Rnf40 | Ccar2 | ENSRNOP00000025500 | ENSRNOP00000024895 | E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] | Cell cycle and apoptosis regulator 2. | 0.568 |
Rnf40 | Edc4 | ENSRNOP00000025500 | ENSRNOP00000006345 | E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] | Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). | 0.643 |