node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cops3 | Drg1 | ENSRNOP00000069208 | ENSRNOP00000025241 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | Developmentally-regulated GTP-binding protein 1. | 0.836 |
Cops3 | Psmc5 | ENSRNOP00000069208 | ENSRNOP00000013997 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | 26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 0.436 |
D4AA59_RAT | Drg1 | ENSRNOP00000071553 | ENSRNOP00000025241 | C3H1-type domain-containing protein. | Developmentally-regulated GTP-binding protein 1. | 0.910 |
D4AA59_RAT | Rell1 | ENSRNOP00000071553 | ENSRNOP00000002984 | C3H1-type domain-containing protein. | Rell1 protein. | 0.424 |
D4AA59_RAT | Rwdd1 | ENSRNOP00000071553 | ENSRNOP00000062656 | C3H1-type domain-containing protein. | RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family. | 0.695 |
D4AA59_RAT | Rwdd4 | ENSRNOP00000071553 | ENSRNOP00000073640 | C3H1-type domain-containing protein. | RWD domain-containing protein 4. | 0.424 |
Drg1 | Cops3 | ENSRNOP00000025241 | ENSRNOP00000069208 | Developmentally-regulated GTP-binding protein 1. | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | 0.836 |
Drg1 | D4AA59_RAT | ENSRNOP00000025241 | ENSRNOP00000071553 | Developmentally-regulated GTP-binding protein 1. | C3H1-type domain-containing protein. | 0.910 |
Drg1 | Mrps7 | ENSRNOP00000025241 | ENSRNOP00000005089 | Developmentally-regulated GTP-binding protein 1. | 28S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family. | 0.766 |
Drg1 | Pole2 | ENSRNOP00000025241 | ENSRNOP00000005835 | Developmentally-regulated GTP-binding protein 1. | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. | 0.740 |
Drg1 | Psmc4 | ENSRNOP00000025241 | ENSRNOP00000025819 | Developmentally-regulated GTP-binding protein 1. | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | 0.825 |
Drg1 | Psmc5 | ENSRNOP00000025241 | ENSRNOP00000013997 | Developmentally-regulated GTP-binding protein 1. | 26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 0.824 |
Drg1 | Rell1 | ENSRNOP00000025241 | ENSRNOP00000002984 | Developmentally-regulated GTP-binding protein 1. | Rell1 protein. | 0.796 |
Drg1 | Rwdd1 | ENSRNOP00000025241 | ENSRNOP00000062656 | Developmentally-regulated GTP-binding protein 1. | RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family. | 0.897 |
Drg1 | Rwdd4 | ENSRNOP00000025241 | ENSRNOP00000073640 | Developmentally-regulated GTP-binding protein 1. | RWD domain-containing protein 4. | 0.798 |
Drg1 | Zc3h15 | ENSRNOP00000025241 | ENSRNOP00000007276 | Developmentally-regulated GTP-binding protein 1. | Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation. Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions. | 0.913 |
Mrps7 | Drg1 | ENSRNOP00000005089 | ENSRNOP00000025241 | 28S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family. | Developmentally-regulated GTP-binding protein 1. | 0.766 |
Pole2 | Drg1 | ENSRNOP00000005835 | ENSRNOP00000025241 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. | Developmentally-regulated GTP-binding protein 1. | 0.740 |
Psmc4 | Drg1 | ENSRNOP00000025819 | ENSRNOP00000025241 | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | Developmentally-regulated GTP-binding protein 1. | 0.825 |
Psmc4 | Psmc5 | ENSRNOP00000025819 | ENSRNOP00000013997 | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | 26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 0.999 |