node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Anpep | Gclc | ENSRNOP00000069456 | ENSRNOP00000035540 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutamate--cysteine ligase catalytic subunit. | 0.942 |
Anpep | Ggct | ENSRNOP00000069456 | ENSRNOP00000049903 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Gamma-glutamyl cyclotransferase. | 0.902 |
Anpep | Ggt5 | ENSRNOP00000069456 | ENSRNOP00000076289 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.937 |
Anpep | Ggt6 | ENSRNOP00000069456 | ENSRNOP00000039691 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates. | 0.951 |
Anpep | Ggt7 | ENSRNOP00000069456 | ENSRNOP00000025315 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.944 |
Anpep | Gsr | ENSRNOP00000069456 | ENSRNOP00000068989 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.429 |
Anpep | Gss | ENSRNOP00000069456 | ENSRNOP00000025657 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | 0.935 |
Anpep | Lap3 | ENSRNOP00000069456 | ENSRNOP00000004770 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity). | 0.959 |
Gclc | Anpep | ENSRNOP00000035540 | ENSRNOP00000069456 | Glutamate--cysteine ligase catalytic subunit. | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | 0.942 |
Gclc | Ggct | ENSRNOP00000035540 | ENSRNOP00000049903 | Glutamate--cysteine ligase catalytic subunit. | Gamma-glutamyl cyclotransferase. | 0.920 |
Gclc | Ggt5 | ENSRNOP00000035540 | ENSRNOP00000076289 | Glutamate--cysteine ligase catalytic subunit. | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.924 |
Gclc | Ggt6 | ENSRNOP00000035540 | ENSRNOP00000039691 | Glutamate--cysteine ligase catalytic subunit. | Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates. | 0.948 |
Gclc | Ggt7 | ENSRNOP00000035540 | ENSRNOP00000025315 | Glutamate--cysteine ligase catalytic subunit. | Glutathione hydrolase 7 heavy chain; Cleaves glutathione conjugates. | 0.931 |
Gclc | Gsr | ENSRNOP00000035540 | ENSRNOP00000068989 | Glutamate--cysteine ligase catalytic subunit. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.896 |
Gclc | Gss | ENSRNOP00000035540 | ENSRNOP00000025657 | Glutamate--cysteine ligase catalytic subunit. | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family. | 0.996 |
Gclc | Lap3 | ENSRNOP00000035540 | ENSRNOP00000004770 | Glutamate--cysteine ligase catalytic subunit. | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity). | 0.902 |
Gclc | Oplah | ENSRNOP00000035540 | ENSRNOP00000074523 | Glutamate--cysteine ligase catalytic subunit. | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate; Belongs to the oxoprolinase family. | 0.955 |
Ggct | Anpep | ENSRNOP00000049903 | ENSRNOP00000069456 | Gamma-glutamyl cyclotransferase. | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] | 0.902 |
Ggct | Gclc | ENSRNOP00000049903 | ENSRNOP00000035540 | Gamma-glutamyl cyclotransferase. | Glutamate--cysteine ligase catalytic subunit. | 0.920 |
Ggct | Ggt5 | ENSRNOP00000049903 | ENSRNOP00000076289 | Gamma-glutamyl cyclotransferase. | Glutathione hydrolase 5 heavy chain; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). | 0.946 |