node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Afdn | Cd226 | ENSRNOP00000029044 | ENSRNOP00000054956 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | CD226 antigen (Predicted), isoform CRA_b. | 0.401 |
Afdn | Nectin1 | ENSRNOP00000029044 | ENSRNOP00000008614 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | Nectin cell adhesion molecule 1. | 0.946 |
Afdn | Nectin2 | ENSRNOP00000029044 | ENSRNOP00000025388 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | Nectin cell adhesion molecule 2. | 0.562 |
Afdn | Nectin3 | ENSRNOP00000029044 | ENSRNOP00000002957 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | Nectin cell adhesion molecule 3. | 0.975 |
Afdn | Nectin4 | ENSRNOP00000029044 | ENSRNOP00000005550 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | Similar to nectin 4 (Predicted), isoform CRA_a. | 0.526 |
Afdn | Pard3 | ENSRNOP00000029044 | ENSRNOP00000048964 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | Partitioning defective 3 homolog; Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (By similarity). Invo [...] | 0.547 |
Afdn | Tomm40 | ENSRNOP00000029044 | ENSRNOP00000025281 | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria. | 0.595 |
Cd226 | Afdn | ENSRNOP00000054956 | ENSRNOP00000029044 | CD226 antigen (Predicted), isoform CRA_b. | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | 0.401 |
Cd226 | Crtam | ENSRNOP00000054956 | ENSRNOP00000010792 | CD226 antigen (Predicted), isoform CRA_b. | Cytotoxic and regulatory T cell molecule. | 0.423 |
Cd226 | Nectin1 | ENSRNOP00000054956 | ENSRNOP00000008614 | CD226 antigen (Predicted), isoform CRA_b. | Nectin cell adhesion molecule 1. | 0.422 |
Cd226 | Nectin2 | ENSRNOP00000054956 | ENSRNOP00000025388 | CD226 antigen (Predicted), isoform CRA_b. | Nectin cell adhesion molecule 2. | 0.900 |
Cd226 | Nectin3 | ENSRNOP00000054956 | ENSRNOP00000002957 | CD226 antigen (Predicted), isoform CRA_b. | Nectin cell adhesion molecule 3. | 0.427 |
Cd226 | Tigit | ENSRNOP00000054956 | ENSRNOP00000074881 | CD226 antigen (Predicted), isoform CRA_b. | T cell immunoreceptor with Ig and ITIM domains. | 0.906 |
Crtam | Cd226 | ENSRNOP00000010792 | ENSRNOP00000054956 | Cytotoxic and regulatory T cell molecule. | CD226 antigen (Predicted), isoform CRA_b. | 0.423 |
Crtam | Nectin2 | ENSRNOP00000010792 | ENSRNOP00000025388 | Cytotoxic and regulatory T cell molecule. | Nectin cell adhesion molecule 2. | 0.900 |
Hsdl2 | Nectin2 | ENSRNOP00000056213 | ENSRNOP00000025388 | Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Nectin cell adhesion molecule 2. | 0.489 |
Nectin1 | Afdn | ENSRNOP00000008614 | ENSRNOP00000029044 | Nectin cell adhesion molecule 1. | Afadin; Belongs to an adhesion system, probably together with the E- cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm (By similarity). Essential for the organization of adherens junctions (By similarity). | 0.946 |
Nectin1 | Cd226 | ENSRNOP00000008614 | ENSRNOP00000054956 | Nectin cell adhesion molecule 1. | CD226 antigen (Predicted), isoform CRA_b. | 0.422 |
Nectin1 | Nectin2 | ENSRNOP00000008614 | ENSRNOP00000025388 | Nectin cell adhesion molecule 1. | Nectin cell adhesion molecule 2. | 0.913 |
Nectin1 | Nectin3 | ENSRNOP00000008614 | ENSRNOP00000002957 | Nectin cell adhesion molecule 1. | Nectin cell adhesion molecule 3. | 0.986 |