STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem223Transmembrane protein 223. (199 aa)    
Predicted Functional Partners:
Pigs
GPI transamidase component PIG-S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity); Belongs to the PIGS family.
   
  
 0.754
Commd10
COMM domain containing 10, isoform CRA_a.
   
  
 0.636
Naa15
NMDA receptor-regulated gene 1 (Predicted), isoform CRA_b.
      
 0.634
Naa20
N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae) (Predicted), isoform CRA_a.
   
  
 0.628
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit.
   
  
 0.617
Atp5mf
ATP synthase subunit f, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...]
   
  
 0.568
Tspan13
Tetraspanin-13.
      
 0.528
Grina
Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.
   
  
 0.522
Zyg11b
Zyg-11 family member B, cell cycle regulator.
      
 0.509
Zer1
Zyg-11-related, cell cycle regulator.
   
  
 0.504
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.