node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ablim3 | Abra | ENSRNOP00000026227 | ENSRNOP00000010539 | Actin-binding LIM protein family, member 3. | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | 0.532 |
Ablim3 | Ccdc136 | ENSRNOP00000026227 | ENSRNOP00000057058 | Actin-binding LIM protein family, member 3. | Coiled-coil domain-containing 136. | 0.456 |
Ablim3 | Cdc42 | ENSRNOP00000026227 | ENSRNOP00000030928 | Actin-binding LIM protein family, member 3. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | 0.912 |
Ablim3 | Csmd2 | ENSRNOP00000026227 | ENSRNOP00000073789 | Actin-binding LIM protein family, member 3. | CUB and Sushi multiple domains 2. | 0.452 |
Ablim3 | Mthfsd | ENSRNOP00000026227 | ENSRNOP00000064613 | Actin-binding LIM protein family, member 3. | Methenyltetrahydrofolate synthetase domain containing. | 0.579 |
Ablim3 | RGD1309534 | ENSRNOP00000026227 | ENSRNOP00000014496 | Actin-binding LIM protein family, member 3. | Ester hydrolase C11orf54 homolog; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | 0.476 |
Ablim3 | Rac1 | ENSRNOP00000026227 | ENSRNOP00000001417 | Actin-binding LIM protein family, member 3. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.908 |
Ablim3 | Rac2 | ENSRNOP00000026227 | ENSRNOP00000009994 | Actin-binding LIM protein family, member 3. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.908 |
Ablim3 | Sh2d4a | ENSRNOP00000026227 | ENSRNOP00000018543 | Actin-binding LIM protein family, member 3. | SH2 domain-containing protein 4A; Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T- cell development and function (By similarity). | 0.564 |
Ablim3 | Tmem217 | ENSRNOP00000026227 | ENSRNOP00000067557 | Actin-binding LIM protein family, member 3. | Transmembrane protein 217-like. | 0.438 |
Abra | Ablim3 | ENSRNOP00000010539 | ENSRNOP00000026227 | Actin-binding Rho-activating protein; Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. | Actin-binding LIM protein family, member 3. | 0.532 |
Ccdc136 | Ablim3 | ENSRNOP00000057058 | ENSRNOP00000026227 | Coiled-coil domain-containing 136. | Actin-binding LIM protein family, member 3. | 0.456 |
Ccdc136 | Tmem217 | ENSRNOP00000057058 | ENSRNOP00000067557 | Coiled-coil domain-containing 136. | Transmembrane protein 217-like. | 0.604 |
Cdc42 | Ablim3 | ENSRNOP00000030928 | ENSRNOP00000026227 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Actin-binding LIM protein family, member 3. | 0.912 |
Cdc42 | Rac1 | ENSRNOP00000030928 | ENSRNOP00000001417 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.954 |
Cdc42 | Rac2 | ENSRNOP00000030928 | ENSRNOP00000009994 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.933 |
Csmd2 | Ablim3 | ENSRNOP00000073789 | ENSRNOP00000026227 | CUB and Sushi multiple domains 2. | Actin-binding LIM protein family, member 3. | 0.452 |
Mthfsd | Ablim3 | ENSRNOP00000064613 | ENSRNOP00000026227 | Methenyltetrahydrofolate synthetase domain containing. | Actin-binding LIM protein family, member 3. | 0.579 |
Mthfsd | Sh2d4a | ENSRNOP00000064613 | ENSRNOP00000018543 | Methenyltetrahydrofolate synthetase domain containing. | SH2 domain-containing protein 4A; Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T- cell development and function (By similarity). | 0.666 |
RGD1309534 | Ablim3 | ENSRNOP00000014496 | ENSRNOP00000026227 | Ester hydrolase C11orf54 homolog; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | Actin-binding LIM protein family, member 3. | 0.476 |