Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atp23 | Dele1 | ENSRNOP00000064274 | ENSRNOP00000026273 | Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family. | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | 0.612 |
| Atp23 | Oma1 | ENSRNOP00000064274 | ENSRNOP00000009515 | Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family. | Metalloendopeptidase OMA1, mitochondrial; Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Belongs to the peptidase [...] | 0.778 |
| Cluh | Dap3 | ENSRNOP00000075826 | ENSRNOP00000072121 | Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family. | Death-associated protein 3. | 0.504 |
| Cluh | Dele1 | ENSRNOP00000075826 | ENSRNOP00000026273 | Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family. | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | 0.543 |
| Cluh | Rbm27 | ENSRNOP00000075826 | ENSRNOP00000035970 | Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family. | RNA-binding motif protein 27. | 0.630 |
| Dap3 | Cluh | ENSRNOP00000072121 | ENSRNOP00000075826 | Death-associated protein 3. | Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family. | 0.504 |
| Dap3 | Dele1 | ENSRNOP00000072121 | ENSRNOP00000026273 | Death-associated protein 3. | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | 0.579 |
| Dele1 | Atp23 | ENSRNOP00000026273 | ENSRNOP00000064274 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family. | 0.612 |
| Dele1 | Cluh | ENSRNOP00000026273 | ENSRNOP00000075826 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family. | 0.543 |
| Dele1 | Dap3 | ENSRNOP00000026273 | ENSRNOP00000072121 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Death-associated protein 3. | 0.579 |
| Dele1 | Eif2ak1 | ENSRNOP00000026273 | ENSRNOP00000001392 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...] | 0.630 |
| Dele1 | Erlec1 | ENSRNOP00000026273 | ENSRNOP00000043115 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Endoplasmic reticulum lectin 1. | 0.626 |
| Dele1 | Has1 | ENSRNOP00000026273 | ENSRNOP00000014824 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Hyaluronan synthase 1. | 0.534 |
| Dele1 | Has2 | ENSRNOP00000026273 | ENSRNOP00000006517 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Hyaluronan synthase 2; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. M [...] | 0.534 |
| Dele1 | Oma1 | ENSRNOP00000026273 | ENSRNOP00000009515 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Metalloendopeptidase OMA1, mitochondrial; Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Belongs to the peptidase [...] | 0.729 |
| Dele1 | Os9 | ENSRNOP00000026273 | ENSRNOP00000044914 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | Protein OS-9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 (By similarity). | 0.615 |
| Dele1 | Rbm27 | ENSRNOP00000026273 | ENSRNOP00000035970 | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | RNA-binding motif protein 27. | 0.631 |
| Eif2ak1 | Dele1 | ENSRNOP00000001392 | ENSRNOP00000026273 | Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...] | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | 0.630 |
| Eif2ak1 | Oma1 | ENSRNOP00000001392 | ENSRNOP00000009515 | Eukaryotic translation initiation factor 2-alpha kinase 1; Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...] | Metalloendopeptidase OMA1, mitochondrial; Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Belongs to the peptidase [...] | 0.418 |
| Erlec1 | Dele1 | ENSRNOP00000043115 | ENSRNOP00000026273 | Endoplasmic reticulum lectin 1. | DAP3-binding cell death enhancer 1; Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. | 0.626 |
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