node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Azin1 | Cog3 | ENSRNOP00000007999 | ENSRNOP00000000168 | Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. | Component of oligomeric golgi complex 3. | 0.651 |
Azin1 | Cyfip2 | ENSRNOP00000007999 | ENSRNOP00000068584 | Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. | Cytoplasmic FMR1-interacting protein 2. | 0.502 |
Azin1 | Tmem63b | ENSRNOP00000007999 | ENSRNOP00000026728 | Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. | Transmembrane protein 63B. | 0.623 |
Cog3 | Azin1 | ENSRNOP00000000168 | ENSRNOP00000007999 | Component of oligomeric golgi complex 3. | Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. | 0.651 |
Cog3 | Cyfip2 | ENSRNOP00000000168 | ENSRNOP00000068584 | Component of oligomeric golgi complex 3. | Cytoplasmic FMR1-interacting protein 2. | 0.731 |
Cog3 | Tmem63b | ENSRNOP00000000168 | ENSRNOP00000026728 | Component of oligomeric golgi complex 3. | Transmembrane protein 63B. | 0.624 |
Cyfip2 | Azin1 | ENSRNOP00000068584 | ENSRNOP00000007999 | Cytoplasmic FMR1-interacting protein 2. | Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. | 0.502 |
Cyfip2 | Cog3 | ENSRNOP00000068584 | ENSRNOP00000000168 | Cytoplasmic FMR1-interacting protein 2. | Component of oligomeric golgi complex 3. | 0.731 |
Cyfip2 | Tmem63b | ENSRNOP00000068584 | ENSRNOP00000026728 | Cytoplasmic FMR1-interacting protein 2. | Transmembrane protein 63B. | 0.679 |
Tcte1 | Tmem63b | ENSRNOP00000027031 | ENSRNOP00000026728 | T-complex-associated testis expressed 1 (Predicted). | Transmembrane protein 63B. | 0.574 |
Tmem120a | Tmem63b | ENSRNOP00000001960 | ENSRNOP00000026728 | Transmembrane protein 120A; Necessary for efficient adipogenesis. | Transmembrane protein 63B. | 0.685 |
Tmem120a | Tmem87a | ENSRNOP00000001960 | ENSRNOP00000063509 | Transmembrane protein 120A; Necessary for efficient adipogenesis. | Transmembrane protein 87A. | 0.715 |
Tmem147 | Tmem63b | ENSRNOP00000028514 | ENSRNOP00000026728 | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | Transmembrane protein 63B. | 0.674 |
Tmem234 | Tmem63b | ENSRNOP00000065748 | ENSRNOP00000026728 | Transmembrane protein 234. | Transmembrane protein 63B. | 0.678 |
Tmem63b | Azin1 | ENSRNOP00000026728 | ENSRNOP00000007999 | Transmembrane protein 63B. | Antizyme inhibitor 1; Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. | 0.623 |
Tmem63b | Cog3 | ENSRNOP00000026728 | ENSRNOP00000000168 | Transmembrane protein 63B. | Component of oligomeric golgi complex 3. | 0.624 |
Tmem63b | Cyfip2 | ENSRNOP00000026728 | ENSRNOP00000068584 | Transmembrane protein 63B. | Cytoplasmic FMR1-interacting protein 2. | 0.679 |
Tmem63b | Tcte1 | ENSRNOP00000026728 | ENSRNOP00000027031 | Transmembrane protein 63B. | T-complex-associated testis expressed 1 (Predicted). | 0.574 |
Tmem63b | Tmem120a | ENSRNOP00000026728 | ENSRNOP00000001960 | Transmembrane protein 63B. | Transmembrane protein 120A; Necessary for efficient adipogenesis. | 0.685 |
Tmem63b | Tmem147 | ENSRNOP00000026728 | ENSRNOP00000028514 | Transmembrane protein 63B. | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.674 |