node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Celf4 | Kctd11 | ENSRNOP00000057864 | ENSRNOP00000020970 | CUGBP, Elav-like family member 4. | Potassium channel tetramerisation domain containing 11 (Predicted). | 0.442 |
Celf4 | Speg | ENSRNOP00000057864 | ENSRNOP00000026941 | CUGBP, Elav-like family member 4. | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.564 |
Chpf | Gmppa | ENSRNOP00000027165 | ENSRNOP00000074442 | Hexosyltransferase. | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | 0.731 |
Chpf | Speg | ENSRNOP00000027165 | ENSRNOP00000026941 | Hexosyltransferase. | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.637 |
Gmppa | Chpf | ENSRNOP00000074442 | ENSRNOP00000027165 | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | Hexosyltransferase. | 0.731 |
Gmppa | Speg | ENSRNOP00000074442 | ENSRNOP00000026941 | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.588 |
Jph2 | Mtm1 | ENSRNOP00000010938 | ENSRNOP00000058761 | Junctophilin-2 N-terminal fragment; [Junctophilin-2]: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. Provides a structural foundation for functional cross- talk between the cell surface and intracellular Ca(2+) release channels by maintaining the 12-15 nm gap between the sarcolemma and the sarcoplasmic reticulum membranes in the cardiac dyads. Necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ry [...] | Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...] | 0.593 |
Jph2 | Speg | ENSRNOP00000010938 | ENSRNOP00000026941 | Junctophilin-2 N-terminal fragment; [Junctophilin-2]: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. Provides a structural foundation for functional cross- talk between the cell surface and intracellular Ca(2+) release channels by maintaining the 12-15 nm gap between the sarcolemma and the sarcoplasmic reticulum membranes in the cardiac dyads. Necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ry [...] | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.578 |
Kctd11 | Celf4 | ENSRNOP00000020970 | ENSRNOP00000057864 | Potassium channel tetramerisation domain containing 11 (Predicted). | CUGBP, Elav-like family member 4. | 0.442 |
Kctd11 | Speg | ENSRNOP00000020970 | ENSRNOP00000026941 | Potassium channel tetramerisation domain containing 11 (Predicted). | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.634 |
Mtm1 | Jph2 | ENSRNOP00000058761 | ENSRNOP00000010938 | Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...] | Junctophilin-2 N-terminal fragment; [Junctophilin-2]: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. Provides a structural foundation for functional cross- talk between the cell surface and intracellular Ca(2+) release channels by maintaining the 12-15 nm gap between the sarcolemma and the sarcoplasmic reticulum membranes in the cardiac dyads. Necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ry [...] | 0.593 |
Mtm1 | Speg | ENSRNOP00000058761 | ENSRNOP00000026941 | Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...] | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.545 |
Pes1 | Speg | ENSRNOP00000005996 | ENSRNOP00000026941 | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.487 |
Pes1 | Wdr18 | ENSRNOP00000005996 | ENSRNOP00000016733 | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | WD repeat-containing protein 18; Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). | 0.933 |
Pitpnb | Speg | ENSRNOP00000050368 | ENSRNOP00000026941 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes. | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.469 |
Sde2 | Speg | ENSRNOP00000075283 | ENSRNOP00000026941 | Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract dama [...] | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.469 |
Speg | Celf4 | ENSRNOP00000026941 | ENSRNOP00000057864 | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | CUGBP, Elav-like family member 4. | 0.564 |
Speg | Chpf | ENSRNOP00000026941 | ENSRNOP00000027165 | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | Hexosyltransferase. | 0.637 |
Speg | Gmppa | ENSRNOP00000026941 | ENSRNOP00000074442 | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | 0.588 |
Speg | Jph2 | ENSRNOP00000026941 | ENSRNOP00000010938 | Striated muscle-specific serine/threonine-protein kinase; Isoform 2 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | Junctophilin-2 N-terminal fragment; [Junctophilin-2]: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. Provides a structural foundation for functional cross- talk between the cell surface and intracellular Ca(2+) release channels by maintaining the 12-15 nm gap between the sarcolemma and the sarcoplasmic reticulum membranes in the cardiac dyads. Necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ry [...] | 0.578 |