STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CoasyCoenzyme A synthase. (563 aa)    
Predicted Functional Partners:
Ppcdc-2
Phosphopantothenoylcysteine decarboxylase (Predicted), isoform CRA_a.
  
 0.999
Ppcs
Phosphopantothenoylcysteine synthetase.
  
 0.991
Ppcdc
Phosphopantothenoylcysteine decarboxylase.
  
 0.991
Ccdc30
Uncharacterized protein.
  
 0.986
Cox19
Similar to 2810437L13Rik protein (Predicted), isoform CRA_c.
  
 0.986
Pank2
Pantothenate kinase 2 (Hallervorden-Spatz syndrome) (Predicted), isoform CRA_a.
    
 0.985
Pank3
Pantothenate kinase 3 (Predicted).
   
 0.967
Pank1
Pantothenate kinase 1 (Predicted), isoform CRA_a.
   
 0.962
Aasdhppt
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN (By similarity).
     
 0.916
Enpp3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...]
   
 
 0.901
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.