node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abca12 | Aloxe3 | ENSRNOP00000054481 | ENSRNOP00000010141 | ATP-binding cassette subfamily A member 12. | Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...] | 0.685 |
Abca12 | Nipal4 | ENSRNOP00000054481 | ENSRNOP00000008544 | ATP-binding cassette subfamily A member 12. | Similar to RIKEN cDNA 9530066K23 (Predicted). | 0.748 |
Abca12 | Pnpla1 | ENSRNOP00000054481 | ENSRNOP00000035242 | ATP-binding cassette subfamily A member 12. | Patatin-like phospholipase domain-containing 1. | 0.640 |
Abca12 | Tgm1 | ENSRNOP00000054481 | ENSRNOP00000027315 | ATP-binding cassette subfamily A member 12. | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. | 0.681 |
Aloxe3 | Abca12 | ENSRNOP00000010141 | ENSRNOP00000054481 | Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...] | ATP-binding cassette subfamily A member 12. | 0.685 |
Aloxe3 | Nipal4 | ENSRNOP00000010141 | ENSRNOP00000008544 | Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...] | Similar to RIKEN cDNA 9530066K23 (Predicted). | 0.758 |
Aloxe3 | Pnpla1 | ENSRNOP00000010141 | ENSRNOP00000035242 | Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...] | Patatin-like phospholipase domain-containing 1. | 0.681 |
Aloxe3 | Tgm1 | ENSRNOP00000010141 | ENSRNOP00000027315 | Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...] | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. | 0.700 |
Cnfn | Evpl | ENSRNOP00000027845 | ENSRNOP00000012373 | Similar to cornifelin (Predicted), isoform CRA_a. | Envoplakin (Predicted). | 0.435 |
Cnfn | Sprr3 | ENSRNOP00000027845 | ENSRNOP00000037841 | Similar to cornifelin (Predicted), isoform CRA_a. | Small proline-rich protein 3 (Predicted). | 0.673 |
Cnfn | Tgm1 | ENSRNOP00000027845 | ENSRNOP00000027315 | Similar to cornifelin (Predicted), isoform CRA_a. | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. | 0.536 |
Dsg1 | Evpl | ENSRNOP00000058060 | ENSRNOP00000012373 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Envoplakin (Predicted). | 0.890 |
Dsg1 | Krt1 | ENSRNOP00000058060 | ENSRNOP00000029276 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity). | 0.652 |
Dsg1 | Ppl | ENSRNOP00000058060 | ENSRNOP00000004026 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Periplakin (Predicted). | 0.871 |
Dsg1 | Tgm1 | ENSRNOP00000058060 | ENSRNOP00000027315 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. | 0.569 |
Evpl | Cnfn | ENSRNOP00000012373 | ENSRNOP00000027845 | Envoplakin (Predicted). | Similar to cornifelin (Predicted), isoform CRA_a. | 0.435 |
Evpl | Dsg1 | ENSRNOP00000012373 | ENSRNOP00000058060 | Envoplakin (Predicted). | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | 0.890 |
Evpl | Krt1 | ENSRNOP00000012373 | ENSRNOP00000029276 | Envoplakin (Predicted). | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity). | 0.410 |
Evpl | Ppl | ENSRNOP00000012373 | ENSRNOP00000004026 | Envoplakin (Predicted). | Periplakin (Predicted). | 0.990 |
Evpl | Tgm1 | ENSRNOP00000012373 | ENSRNOP00000027315 | Envoplakin (Predicted). | Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. | 0.635 |