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Tead2 protein (Rattus norvegicus) - STRING interaction network
"Tead2" - TEA domain family member 2 in Rattus norvegicus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tead2TEA domain family member 2 (445 aa)    
Predicted Functional Partners:
Yap1
Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncopro [...] (362 aa)
     
  0.989
Wwtr1
Transcriptional co-activator with PDZ-binding motif (TA)Z, isoform CRA_b; WW domain containing transcription regulator 1 (395 aa)
     
  0.987
Tead1
TEA domain family member 1 (415 aa)
     
0.977
Tead4
TEA domain family member 4 (427 aa)
     
0.971
Tead3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (437 aa)
     
0.962
Runx3
Runt-related transcription factor; CBF binds to the core site, 5’-PYGPYGGT-3’, of a number of enhancers and promoters (409 aa)
         
  0.903
Tcf7l1
Transcription factor 7-like 1 (T-cell specific, HMG-box) (587 aa)
     
 
  0.851
Tcf7l2
Transcription factor 7-like 2 (T-cell specific, HMG-box) (414 aa)
     
 
  0.845
Lef1
Lymphoid enhancer-binding factor 1; Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIASG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity) (397 aa)
     
 
  0.816
Tcf7
Transcription factor 7 (T-cell specific, HMG-box) (419 aa)
     
 
  0.815
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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