node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arl4d | Cyth2 | ENSRNOP00000028178 | ENSRNOP00000028588 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | 0.654 |
Arl4d | Flna | ENSRNOP00000028178 | ENSRNOP00000070703 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Filamin, alpha (Predicted), isoform CRA_a. | 0.517 |
Arl4d | Itsn1 | ENSRNOP00000028178 | ENSRNOP00000044773 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | 0.590 |
Arl4d | Itsn2 | ENSRNOP00000028178 | ENSRNOP00000065329 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Intersectin 2. | 0.665 |
Arl4d | Klf10 | ENSRNOP00000028178 | ENSRNOP00000008350 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Krueppel-like factor 10; Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation (By similarity). Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Belongs to the Sp1 C2H2-type zinc-finger prote [...] | 0.436 |
Arl4d | Mfap3 | ENSRNOP00000028178 | ENSRNOP00000003361 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Microfibril-associated glycoprotein 3; Component of the elastin-associated microfibrils. | 0.497 |
Arl4d | Morn4 | ENSRNOP00000028178 | ENSRNOP00000032408 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | MORN repeat-containing protein 4; Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma. | 0.536 |
Arl4d | Nol6 | ENSRNOP00000028178 | ENSRNOP00000060015 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Nucleolar protein 6. | 0.516 |
Arl4d | Nrn1 | ENSRNOP00000028178 | ENSRNOP00000066878 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Neuritin; Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. Belongs to the neuritin family. | 0.424 |
Arl4d | Slc25a45 | ENSRNOP00000028178 | ENSRNOP00000041281 | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | Solute carrier family 25, member 45; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.441 |
Cyth2 | Arl4d | ENSRNOP00000028588 | ENSRNOP00000028178 | Cytohesin-2; Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity). | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | 0.654 |
Flna | Arl4d | ENSRNOP00000070703 | ENSRNOP00000028178 | Filamin, alpha (Predicted), isoform CRA_a. | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | 0.517 |
Itsn1 | Arl4d | ENSRNOP00000044773 | ENSRNOP00000028178 | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | 0.590 |
Itsn1 | Itsn2 | ENSRNOP00000044773 | ENSRNOP00000065329 | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | Intersectin 2. | 0.618 |
Itsn2 | Arl4d | ENSRNOP00000065329 | ENSRNOP00000028178 | Intersectin 2. | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | 0.665 |
Itsn2 | Itsn1 | ENSRNOP00000065329 | ENSRNOP00000044773 | Intersectin 2. | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | 0.618 |
Klf10 | Arl4d | ENSRNOP00000008350 | ENSRNOP00000028178 | Krueppel-like factor 10; Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation (By similarity). Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Belongs to the Sp1 C2H2-type zinc-finger prote [...] | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | 0.436 |
Mfap3 | Arl4d | ENSRNOP00000003361 | ENSRNOP00000028178 | Microfibril-associated glycoprotein 3; Component of the elastin-associated microfibrils. | ADP-ribosylation factor 4-like (Predicted); Belongs to the small GTPase superfamily. Arf family. | 0.497 |
Mfap3 | Morn4 | ENSRNOP00000003361 | ENSRNOP00000032408 | Microfibril-associated glycoprotein 3; Component of the elastin-associated microfibrils. | MORN repeat-containing protein 4; Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma. | 0.754 |
Mfap3 | Nol6 | ENSRNOP00000003361 | ENSRNOP00000060015 | Microfibril-associated glycoprotein 3; Component of the elastin-associated microfibrils. | Nucleolar protein 6. | 0.731 |