node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hsd17b14 | Plekha4 | ENSRNOP00000028436 | ENSRNOP00000028423 | Hydroxysteroid (17-beta) dehydrogenase 14. | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.510 |
Hsd17b14 | Pnma8a | ENSRNOP00000028436 | ENSRNOP00000034811 | Hydroxysteroid (17-beta) dehydrogenase 14. | PNMA family member 8A. | 0.574 |
Hsd17b14 | Pnma8b | ENSRNOP00000028436 | ENSRNOP00000022610 | Hydroxysteroid (17-beta) dehydrogenase 14. | Similar to KIAA1183 protein (Predicted). | 0.562 |
Klhl12 | Pdzd11 | ENSRNOP00000005832 | ENSRNOP00000067975 | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | PDZ domain containing 11 (Predicted), isoform CRA_c. | 0.501 |
Klhl12 | Plekha4 | ENSRNOP00000005832 | ENSRNOP00000028423 | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.726 |
Klhl12 | Uba52 | ENSRNOP00000005832 | ENSRNOP00000027073 | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.520 |
Nme7 | Plekha4 | ENSRNOP00000055684 | ENSRNOP00000028423 | Nucleoside diphosphate kinase 7; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.572 |
Pdzd11 | Klhl12 | ENSRNOP00000067975 | ENSRNOP00000005832 | PDZ domain containing 11 (Predicted), isoform CRA_c. | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | 0.501 |
Pdzd11 | Plekha4 | ENSRNOP00000067975 | ENSRNOP00000028423 | PDZ domain containing 11 (Predicted), isoform CRA_c. | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.607 |
Pdzd11 | Uba52 | ENSRNOP00000067975 | ENSRNOP00000027073 | PDZ domain containing 11 (Predicted), isoform CRA_c. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.483 |
Plekha2 | Plekha3 | ENSRNOP00000022097 | ENSRNOP00000016132 | Pleckstrin homology domain-containing A2. | Pleckstrin homology domain-containing A3. | 0.671 |
Plekha2 | Plekha4 | ENSRNOP00000022097 | ENSRNOP00000028423 | Pleckstrin homology domain-containing A2. | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.601 |
Plekha2 | Uba52 | ENSRNOP00000022097 | ENSRNOP00000027073 | Pleckstrin homology domain-containing A2. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.452 |
Plekha3 | Plekha2 | ENSRNOP00000016132 | ENSRNOP00000022097 | Pleckstrin homology domain-containing A3. | Pleckstrin homology domain-containing A2. | 0.671 |
Plekha3 | Plekha4 | ENSRNOP00000016132 | ENSRNOP00000028423 | Pleckstrin homology domain-containing A3. | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | 0.651 |
Plekha4 | Hsd17b14 | ENSRNOP00000028423 | ENSRNOP00000028436 | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | Hydroxysteroid (17-beta) dehydrogenase 14. | 0.510 |
Plekha4 | Klhl12 | ENSRNOP00000028423 | ENSRNOP00000005832 | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | 0.726 |
Plekha4 | Nme7 | ENSRNOP00000028423 | ENSRNOP00000055684 | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | Nucleoside diphosphate kinase 7; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.572 |
Plekha4 | Pdzd11 | ENSRNOP00000028423 | ENSRNOP00000067975 | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | PDZ domain containing 11 (Predicted), isoform CRA_c. | 0.607 |
Plekha4 | Plekha2 | ENSRNOP00000028423 | ENSRNOP00000022097 | Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. | Pleckstrin homology domain-containing A2. | 0.601 |