node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc47 | Ncln | ENSRNOP00000012533 | ENSRNOP00000007110 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 0.876 |
Ccdc47 | Rpl13a | ENSRNOP00000012533 | ENSRNOP00000027976 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppres [...] | 0.727 |
Ccdc47 | Rpl22 | ENSRNOP00000012533 | ENSRNOP00000014905 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 60S ribosomal protein L22. | 0.709 |
Ccdc47 | Rpl23 | ENSRNOP00000012533 | ENSRNOP00000005471 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.712 |
Ccdc47 | Rpl4 | ENSRNOP00000012533 | ENSRNOP00000013462 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. | 0.718 |
Ccdc47 | Sec61b | ENSRNOP00000012533 | ENSRNOP00000008329 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.728 |
Ccdc47 | Tmco1 | ENSRNOP00000012533 | ENSRNOP00000074404 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store. | 0.899 |
Ccdc47 | Tmem147 | ENSRNOP00000012533 | ENSRNOP00000028514 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.863 |
Galm | Ncln | ENSRNOP00000009221 | ENSRNOP00000007110 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 0.471 |
Galm | Tmem147 | ENSRNOP00000009221 | ENSRNOP00000028514 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.748 |
Galm | Tmem63a | ENSRNOP00000009221 | ENSRNOP00000069668 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | Transmembrane protein 63a. | 0.739 |
Ncln | Ccdc47 | ENSRNOP00000007110 | ENSRNOP00000012533 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 0.876 |
Ncln | Galm | ENSRNOP00000007110 | ENSRNOP00000009221 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | 0.471 |
Ncln | Rpl13a | ENSRNOP00000007110 | ENSRNOP00000027976 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppres [...] | 0.709 |
Ncln | Rpl22 | ENSRNOP00000007110 | ENSRNOP00000014905 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 60S ribosomal protein L22. | 0.709 |
Ncln | Rpl23 | ENSRNOP00000007110 | ENSRNOP00000005471 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.709 |
Ncln | Rpl4 | ENSRNOP00000007110 | ENSRNOP00000013462 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. | 0.728 |
Ncln | Sec61b | ENSRNOP00000007110 | ENSRNOP00000008329 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.712 |
Ncln | Tmco1 | ENSRNOP00000007110 | ENSRNOP00000074404 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store. | 0.841 |
Ncln | Tmem147 | ENSRNOP00000007110 | ENSRNOP00000028514 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.941 |