STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nomo1Similar to pM5 protein; DNA segment, Chr 7, ERATO Doi 156, expressed (Predicted). (1214 aa)    
Predicted Functional Partners:
Ncln
Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
   
 
 0.861
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit.
      
 0.612
Prr12
Proline-rich 12.
      
 0.571
Tmem147
Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity).
   
 
 0.562
Abracl
RCG57402, isoform CRA_b.
      
 0.562
Hint2
Histidine triad nucleotide binding protein 2 (Predicted), isoform CRA_a.
   
  
 0.560
Nepn
Similar to RIKEN cDNA 5730521E12 (Predicted), isoform CRA_b.
      
 0.533
Plpbp
Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
   
  
 0.510
Fam136a
Protein FAM136A; Belongs to the FAM136 family.
      
 0.504
Tmx4
Thioredoxin-related transmembrane protein 4.
   
 
 0.503
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.