node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Kcnk12 | Kcnk13 | ENSRNOP00000021570 | ENSRNOP00000067310 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | 0.652 |
Kcnk12 | Kcnk15 | ENSRNOP00000021570 | ENSRNOP00000014411 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | 0.674 |
Kcnk12 | Kcnk2 | ENSRNOP00000021570 | ENSRNOP00000003684 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled recep [...] | 0.646 |
Kcnk12 | Kcnk3 | ENSRNOP00000021570 | ENSRNOP00000013107 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward. | 0.671 |
Kcnk12 | Kcnk4 | ENSRNOP00000021570 | ENSRNOP00000028704 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Potassium channel subfamily K member 4; Voltage-insensitive potassium channel. Channel opening is triggered by mechanical forces that deform the membrane, and by raising the intracellular pH to basic levels. The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius. Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure ( [...] | 0.765 |
Kcnk12 | Kcnk9 | ENSRNOP00000021570 | ENSRNOP00000012408 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.687 |
Kcnk12 | Kcnma1 | ENSRNOP00000021570 | ENSRNOP00000058962 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | 0.432 |
Kcnk13 | Kcnk12 | ENSRNOP00000067310 | ENSRNOP00000021570 | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.652 |
Kcnk13 | Kcnk15 | ENSRNOP00000067310 | ENSRNOP00000014411 | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | 0.635 |
Kcnk13 | Kcnk2 | ENSRNOP00000067310 | ENSRNOP00000003684 | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled recep [...] | 0.648 |
Kcnk13 | Kcnk3 | ENSRNOP00000067310 | ENSRNOP00000013107 | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward. | 0.641 |
Kcnk13 | Kcnk4 | ENSRNOP00000067310 | ENSRNOP00000028704 | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | Potassium channel subfamily K member 4; Voltage-insensitive potassium channel. Channel opening is triggered by mechanical forces that deform the membrane, and by raising the intracellular pH to basic levels. The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius. Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure ( [...] | 0.743 |
Kcnk13 | Kcnk9 | ENSRNOP00000067310 | ENSRNOP00000012408 | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.653 |
Kcnk15 | Kcnk12 | ENSRNOP00000014411 | ENSRNOP00000021570 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.674 |
Kcnk15 | Kcnk13 | ENSRNOP00000014411 | ENSRNOP00000067310 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | Potassium channel subfamily K member 13; Potassium channel displaying weak inward rectification in symmetrical K(+) solution. | 0.635 |
Kcnk15 | Kcnk2 | ENSRNOP00000014411 | ENSRNOP00000003684 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled recep [...] | 0.647 |
Kcnk15 | Kcnk3 | ENSRNOP00000014411 | ENSRNOP00000013107 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward. | 0.535 |
Kcnk15 | Kcnk4 | ENSRNOP00000014411 | ENSRNOP00000028704 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | Potassium channel subfamily K member 4; Voltage-insensitive potassium channel. Channel opening is triggered by mechanical forces that deform the membrane, and by raising the intracellular pH to basic levels. The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius. Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure ( [...] | 0.681 |
Kcnk15 | Kcnk9 | ENSRNOP00000014411 | ENSRNOP00000012408 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel. | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.627 |
Kcnk2 | Kcnk12 | ENSRNOP00000003684 | ENSRNOP00000021570 | Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled recep [...] | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.646 |