node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bmp4 | Edar | ENSRNOP00000012957 | ENSRNOP00000029258 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | Ectodysplasin-A receptor. | 0.671 |
Bmp4 | Odam | ENSRNOP00000012957 | ENSRNOP00000035991 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family. | 0.599 |
Bmp4 | Pax9 | ENSRNOP00000012957 | ENSRNOP00000011802 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. | 0.623 |
Bmp4 | Shh | ENSRNOP00000012957 | ENSRNOP00000008497 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.814 |
Bmp4 | Wnt10a | ENSRNOP00000012957 | ENSRNOP00000072067 | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.460 |
Cyb5d1 | Edar | ENSRNOP00000066788 | ENSRNOP00000029258 | Cytochrome b5 domain-containing 1; Belongs to the cytochrome b5 family. | Ectodysplasin-A receptor. | 0.648 |
Eda | Edar | ENSRNOP00000067997 | ENSRNOP00000029258 | Ectodysplasin-A; Belongs to the tumor necrosis factor family. | Ectodysplasin-A receptor. | 0.934 |
Eda | Edaradd | ENSRNOP00000067997 | ENSRNOP00000003535 | Ectodysplasin-A; Belongs to the tumor necrosis factor family. | Similar to crinkled (Predicted). | 0.666 |
Edar | Bmp4 | ENSRNOP00000029258 | ENSRNOP00000012957 | Ectodysplasin-A receptor. | Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). | 0.671 |
Edar | Cyb5d1 | ENSRNOP00000029258 | ENSRNOP00000066788 | Ectodysplasin-A receptor. | Cytochrome b5 domain-containing 1; Belongs to the cytochrome b5 family. | 0.648 |
Edar | Eda | ENSRNOP00000029258 | ENSRNOP00000067997 | Ectodysplasin-A receptor. | Ectodysplasin-A; Belongs to the tumor necrosis factor family. | 0.934 |
Edar | Edaradd | ENSRNOP00000029258 | ENSRNOP00000003535 | Ectodysplasin-A receptor. | Similar to crinkled (Predicted). | 0.994 |
Edar | Odam | ENSRNOP00000029258 | ENSRNOP00000035991 | Ectodysplasin-A receptor. | Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family. | 0.663 |
Edar | Pax9 | ENSRNOP00000029258 | ENSRNOP00000011802 | Ectodysplasin-A receptor. | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. | 0.556 |
Edar | Shh | ENSRNOP00000029258 | ENSRNOP00000008497 | Ectodysplasin-A receptor. | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.598 |
Edar | Slc24a5 | ENSRNOP00000029258 | ENSRNOP00000048644 | Ectodysplasin-A receptor. | Solute carrier family 24, member 5 (Predicted); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.558 |
Edar | Use1 | ENSRNOP00000029258 | ENSRNOP00000022650 | Ectodysplasin-A receptor. | Unconventional SNARE in the ER 1. | 0.564 |
Edar | Wnt10a | ENSRNOP00000029258 | ENSRNOP00000072067 | Ectodysplasin-A receptor. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.569 |
Edaradd | Eda | ENSRNOP00000003535 | ENSRNOP00000067997 | Similar to crinkled (Predicted). | Ectodysplasin-A; Belongs to the tumor necrosis factor family. | 0.666 |
Edaradd | Edar | ENSRNOP00000003535 | ENSRNOP00000029258 | Similar to crinkled (Predicted). | Ectodysplasin-A receptor. | 0.994 |