Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mepce | Ppm1g | ENSRNOP00000067286 | ENSRNOP00000029414 | Methylphosphate capping enzyme. | Protein phosphatase 1G. | 0.557 |
| Mmgt1 | Ppm1g | ENSRNOP00000001179 | ENSRNOP00000029414 | Membrane magnesium transporter 1; Mediates Mg(2+) transport. | Protein phosphatase 1G. | 0.552 |
| Nt5dc2 | Ppm1g | ENSRNOP00000024840 | ENSRNOP00000029414 | 5'-nucleotidase domain-containing protein 2. | Protein phosphatase 1G. | 0.537 |
| Ppm1g | Mepce | ENSRNOP00000029414 | ENSRNOP00000067286 | Protein phosphatase 1G. | Methylphosphate capping enzyme. | 0.557 |
| Ppm1g | Mmgt1 | ENSRNOP00000029414 | ENSRNOP00000001179 | Protein phosphatase 1G. | Membrane magnesium transporter 1; Mediates Mg(2+) transport. | 0.552 |
| Ppm1g | Nt5dc2 | ENSRNOP00000029414 | ENSRNOP00000024840 | Protein phosphatase 1G. | 5'-nucleotidase domain-containing protein 2. | 0.537 |
| Ppm1g | Ppp1r15b | ENSRNOP00000029414 | ENSRNOP00000034252 | Protein phosphatase 1G. | Protein phosphatase 1, regulatory (Inhibitor) subunit 15b (Predicted). | 0.545 |
| Ppm1g | Ppp6c | ENSRNOP00000029414 | ENSRNOP00000021176 | Protein phosphatase 1G. | Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. Participates also in the innate immune defense against viruses by desphosphorylating RIG-I/DDX58, an essential [...] | 0.614 |
| Ppm1g | Sac3d1 | ENSRNOP00000029414 | ENSRNOP00000028509 | Protein phosphatase 1G. | SAC3 domain containing 1. | 0.657 |
| Ppm1g | Thrap3 | ENSRNOP00000029414 | ENSRNOP00000013570 | Protein phosphatase 1G. | Thyroid hormone receptor-associated protein 3; Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin- D1/CCND1 mRNA [...] | 0.547 |
| Ppm1g | Trip12 | ENSRNOP00000029414 | ENSRNOP00000068991 | Protein phosphatase 1G. | E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spr [...] | 0.559 |
| Ppm1g | Usp7 | ENSRNOP00000029414 | ENSRNOP00000041134 | Protein phosphatase 1G. | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN, KMT2E/MLL5 and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation (By similarity). Deubiquitinates p53/TP53, preventing degradation of p53/TP53, and enhances p53/TP53-dependent transcription regulation, cell growth repression and apoptosis (By similarity). Deubiquitinates p53/TP53 and MDM2 and strongly s [...] | 0.679 |
| Ppm1g | Wwp2 | ENSRNOP00000029414 | ENSRNOP00000018837 | Protein phosphatase 1G. | WW domain-containing E3 ubiquitin protein ligase 2. | 0.618 |
| Ppp1r15b | Ppm1g | ENSRNOP00000034252 | ENSRNOP00000029414 | Protein phosphatase 1, regulatory (Inhibitor) subunit 15b (Predicted). | Protein phosphatase 1G. | 0.545 |
| Ppp6c | Ppm1g | ENSRNOP00000021176 | ENSRNOP00000029414 | Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. Participates also in the innate immune defense against viruses by desphosphorylating RIG-I/DDX58, an essential [...] | Protein phosphatase 1G. | 0.614 |
| Sac3d1 | Ppm1g | ENSRNOP00000028509 | ENSRNOP00000029414 | SAC3 domain containing 1. | Protein phosphatase 1G. | 0.657 |
| Thrap3 | Ppm1g | ENSRNOP00000013570 | ENSRNOP00000029414 | Thyroid hormone receptor-associated protein 3; Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin- D1/CCND1 mRNA [...] | Protein phosphatase 1G. | 0.547 |
| Trip12 | Ppm1g | ENSRNOP00000068991 | ENSRNOP00000029414 | E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spr [...] | Protein phosphatase 1G. | 0.559 |
| Trip12 | Usp7 | ENSRNOP00000068991 | ENSRNOP00000041134 | E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spr [...] | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN, KMT2E/MLL5 and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation (By similarity). Deubiquitinates p53/TP53, preventing degradation of p53/TP53, and enhances p53/TP53-dependent transcription regulation, cell growth repression and apoptosis (By similarity). Deubiquitinates p53/TP53 and MDM2 and strongly s [...] | 0.905 |
| Usp7 | Ppm1g | ENSRNOP00000041134 | ENSRNOP00000029414 | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN, KMT2E/MLL5 and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation (By similarity). Deubiquitinates p53/TP53, preventing degradation of p53/TP53, and enhances p53/TP53-dependent transcription regulation, cell growth repression and apoptosis (By similarity). Deubiquitinates p53/TP53 and MDM2 and strongly s [...] | Protein phosphatase 1G. | 0.679 |
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