STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cep295Centrosomal protein of 295 kDa; Centriole-enriched microtubule-binding protein involved in centriole biogenesis. Essential for the generation of the distal portion of new-born centrioles in a CENPJ- and CEP120-mediated elongation dependent manner during the cell cycle S/G2 phase after formation of the initiating cartwheel structure. Required for the recruitment of centriolar proteins, such as POC1B, POC5 and CEP135, into the distal portion of centrioles. Also required for centriole-to- centrosome conversion during mitotic progression, but is dispensable for cartwheel removal or centrio [...] (2473 aa)    
Predicted Functional Partners:
Rbm34
RNA-binding protein 34.
   
  
 0.698
LOC100910581
Protein phosphatase 1 regulatory subunit 35-like.
      
 0.696
Ppp1r35
Protein phosphatase 1 regulatory subunit 35-like.
      
 0.694
Cep126
Centrosomal protein 126.
      
 0.634
Ccdc190
Similar to novel protein (Predicted).
      
 0.614
Rttn
Rotatin.
    
 
 0.603
Cep135
Centrosomal protein 135.
   
 
 0.599
Minar2
Membrane integral NOTCH2-associated receptor 2.
      
 0.588
Tsga10
Testis-specific gene 10 protein; Plays a role in spermatogenesis (By similarity). When overexpressed, prevents nuclear localization of HIF1A (By similarity). Belongs to the CEP135/TSGA10 family.
   
 
 0.582
Vwa5b2
Von Willebrand factor A domain-containing 5B2.
      
 0.571
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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