node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acan | Bgn | ENSRNOP00000042691 | ENSRNOP00000072449 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Biglycan; May be involved in collagen fiber assembly. | 0.882 |
Acan | Col1a1 | ENSRNOP00000042691 | ENSRNOP00000005311 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.767 |
Acan | Dcn | ENSRNOP00000042691 | ENSRNOP00000006070 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Decorin; May affect the rate of fibrils formation (By similarity). May be implicated in the dilatation of the rat cervix. | 0.920 |
Acan | Fmod | ENSRNOP00000042691 | ENSRNOP00000004382 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.922 |
Acan | Gdf5 | ENSRNOP00000042691 | ENSRNOP00000066703 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Growth differentiation factor 5. | 0.703 |
Acan | Gdf6 | ENSRNOP00000042691 | ENSRNOP00000010266 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Growth/differentiation factor 6; Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal- ventral positional information in the retina and controls the formation of the retinotectal map. Required for normal formation of bones and joints in the limbs, skull, digits and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. Regulation of GDF6 expression seems to be a mechanism for evolving species-speci [...] | 0.521 |
Acan | Mkx | ENSRNOP00000042691 | ENSRNOP00000025623 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Mohawk homeobox. | 0.507 |
Acan | Scx | ENSRNOP00000042691 | ENSRNOP00000029792 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Scleraxis bHLH transcription factor. | 0.586 |
Acan | Sox9 | ENSRNOP00000042691 | ENSRNOP00000003511 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | SRY-box transcription factor 9. | 0.903 |
Acan | Tnmd | ENSRNOP00000042691 | ENSRNOP00000073972 | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | Tenomodulin; May be an angiogenesis inhibitor. | 0.712 |
Bgn | Acan | ENSRNOP00000072449 | ENSRNOP00000042691 | Biglycan; May be involved in collagen fiber assembly. | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | 0.882 |
Bgn | Col1a1 | ENSRNOP00000072449 | ENSRNOP00000005311 | Biglycan; May be involved in collagen fiber assembly. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.900 |
Bgn | Dcn | ENSRNOP00000072449 | ENSRNOP00000006070 | Biglycan; May be involved in collagen fiber assembly. | Decorin; May affect the rate of fibrils formation (By similarity). May be implicated in the dilatation of the rat cervix. | 0.973 |
Bgn | Fmod | ENSRNOP00000072449 | ENSRNOP00000004382 | Biglycan; May be involved in collagen fiber assembly. | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.944 |
Bgn | Gdf5 | ENSRNOP00000072449 | ENSRNOP00000066703 | Biglycan; May be involved in collagen fiber assembly. | Growth differentiation factor 5. | 0.450 |
Bgn | Mkx | ENSRNOP00000072449 | ENSRNOP00000025623 | Biglycan; May be involved in collagen fiber assembly. | Mohawk homeobox. | 0.634 |
Bgn | Scx | ENSRNOP00000072449 | ENSRNOP00000029792 | Biglycan; May be involved in collagen fiber assembly. | Scleraxis bHLH transcription factor. | 0.565 |
Bgn | Sox9 | ENSRNOP00000072449 | ENSRNOP00000003511 | Biglycan; May be involved in collagen fiber assembly. | SRY-box transcription factor 9. | 0.508 |
Bgn | Tnmd | ENSRNOP00000072449 | ENSRNOP00000073972 | Biglycan; May be involved in collagen fiber assembly. | Tenomodulin; May be an angiogenesis inhibitor. | 0.743 |
Col1a1 | Acan | ENSRNOP00000005311 | ENSRNOP00000042691 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. | 0.767 |