node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adcy3 | Ano2 | ENSRNOP00000005389 | ENSRNOP00000070208 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Anoctamin. | 0.647 |
Adcy3 | Cnga2 | ENSRNOP00000005389 | ENSRNOP00000016415 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | 0.840 |
Adcy3 | Cnga4 | ENSRNOP00000005389 | ENSRNOP00000023751 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Cyclic nucleotide-gated cation channel alpha-4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). | 0.712 |
Adcy3 | Gnal | ENSRNOP00000005389 | ENSRNOP00000073266 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters; Belongs to the G-alpha family. G(s) subfamily. | 0.977 |
Adcy3 | Ric8b | ENSRNOP00000005389 | ENSRNOP00000069306 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction (Probable). | 0.571 |
Adcy3 | Rtp1 | ENSRNOP00000005389 | ENSRNOP00000029915 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Receptor (chemosensory) transporter protein 1. | 0.676 |
Ano2 | Adcy3 | ENSRNOP00000070208 | ENSRNOP00000005389 | Anoctamin. | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.647 |
Ano2 | Cnga2 | ENSRNOP00000070208 | ENSRNOP00000016415 | Anoctamin. | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | 0.775 |
Ano2 | Cnga4 | ENSRNOP00000070208 | ENSRNOP00000023751 | Anoctamin. | Cyclic nucleotide-gated cation channel alpha-4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). | 0.704 |
Ano2 | Gnal | ENSRNOP00000070208 | ENSRNOP00000073266 | Anoctamin. | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters; Belongs to the G-alpha family. G(s) subfamily. | 0.550 |
Ano2 | Reep1 | ENSRNOP00000070208 | ENSRNOP00000061062 | Anoctamin. | Receptor expression-enhancing protein. | 0.468 |
Ano2 | Ric8b | ENSRNOP00000070208 | ENSRNOP00000069306 | Anoctamin. | Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction (Probable). | 0.479 |
Ano2 | Rtp1 | ENSRNOP00000070208 | ENSRNOP00000029915 | Anoctamin. | Receptor (chemosensory) transporter protein 1. | 0.698 |
Cnga2 | Adcy3 | ENSRNOP00000016415 | ENSRNOP00000005389 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.840 |
Cnga2 | Ano2 | ENSRNOP00000016415 | ENSRNOP00000070208 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Anoctamin. | 0.775 |
Cnga2 | Cnga4 | ENSRNOP00000016415 | ENSRNOP00000023751 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Cyclic nucleotide-gated cation channel alpha-4; Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). | 0.994 |
Cnga2 | Gnal | ENSRNOP00000016415 | ENSRNOP00000073266 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters; Belongs to the G-alpha family. G(s) subfamily. | 0.757 |
Cnga2 | LOC686683 | ENSRNOP00000016415 | ENSRNOP00000073231 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Olfactory receptor. | 0.465 |
Cnga2 | Reep1 | ENSRNOP00000016415 | ENSRNOP00000061062 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Receptor expression-enhancing protein. | 0.473 |
Cnga2 | Ric8b | ENSRNOP00000016415 | ENSRNOP00000069306 | Cyclic nucleotide-gated olfactory channel; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. | Synembryn-B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction (Probable). | 0.605 |