node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Birc2 | Birc3 | ENSRNOP00000014560 | ENSRNOP00000007702 | Baculoviral IAP repeat-containing 2. | Baculoviral IAP repeat-containing 3. | 0.983 |
Birc2 | Birc5 | ENSRNOP00000014560 | ENSRNOP00000065784 | Baculoviral IAP repeat-containing 2. | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.934 |
Birc2 | Diablo | ENSRNOP00000014560 | ENSRNOP00000046476 | Baculoviral IAP repeat-containing 2. | Diablo homolog (Drosophila), isoform CRA_b. | 0.989 |
Birc2 | Htra2 | ENSRNOP00000014560 | ENSRNOP00000030076 | Baculoviral IAP repeat-containing 2. | HtrA serine peptidase 2. | 0.976 |
Birc2 | Tnfrsf1a | ENSRNOP00000014560 | ENSRNOP00000042371 | Baculoviral IAP repeat-containing 2. | Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). | 0.979 |
Birc2 | Traf2 | ENSRNOP00000014560 | ENSRNOP00000008253 | Baculoviral IAP repeat-containing 2. | TNF receptor-associated factor. | 0.997 |
Birc2 | Xiap | ENSRNOP00000014560 | ENSRNOP00000071268 | Baculoviral IAP repeat-containing 2. | E3 ubiquitin-protein ligase XIAP; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and the target proteins for its E3 ubiquitin-protein ligas [...] | 0.971 |
Birc3 | Birc2 | ENSRNOP00000007702 | ENSRNOP00000014560 | Baculoviral IAP repeat-containing 3. | Baculoviral IAP repeat-containing 2. | 0.983 |
Birc3 | Birc5 | ENSRNOP00000007702 | ENSRNOP00000065784 | Baculoviral IAP repeat-containing 3. | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.936 |
Birc3 | Cycs | ENSRNOP00000007702 | ENSRNOP00000014058 | Baculoviral IAP repeat-containing 3. | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.426 |
Birc3 | Diablo | ENSRNOP00000007702 | ENSRNOP00000046476 | Baculoviral IAP repeat-containing 3. | Diablo homolog (Drosophila), isoform CRA_b. | 0.989 |
Birc3 | Htra2 | ENSRNOP00000007702 | ENSRNOP00000030076 | Baculoviral IAP repeat-containing 3. | HtrA serine peptidase 2. | 0.975 |
Birc3 | Tnfrsf1a | ENSRNOP00000007702 | ENSRNOP00000042371 | Baculoviral IAP repeat-containing 3. | Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). | 0.989 |
Birc3 | Traf2 | ENSRNOP00000007702 | ENSRNOP00000008253 | Baculoviral IAP repeat-containing 3. | TNF receptor-associated factor. | 0.998 |
Birc3 | Xiap | ENSRNOP00000007702 | ENSRNOP00000071268 | Baculoviral IAP repeat-containing 3. | E3 ubiquitin-protein ligase XIAP; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and the target proteins for its E3 ubiquitin-protein ligas [...] | 0.971 |
Birc5 | Birc2 | ENSRNOP00000065784 | ENSRNOP00000014560 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Baculoviral IAP repeat-containing 2. | 0.934 |
Birc5 | Birc3 | ENSRNOP00000065784 | ENSRNOP00000007702 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Baculoviral IAP repeat-containing 3. | 0.936 |
Birc5 | Diablo | ENSRNOP00000065784 | ENSRNOP00000046476 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Diablo homolog (Drosophila), isoform CRA_b. | 0.978 |
Birc5 | Htra2 | ENSRNOP00000065784 | ENSRNOP00000030076 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | HtrA serine peptidase 2. | 0.928 |
Birc5 | Xiap | ENSRNOP00000065784 | ENSRNOP00000071268 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | E3 ubiquitin-protein ligase XIAP; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and the target proteins for its E3 ubiquitin-protein ligas [...] | 0.782 |