STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NrapNebulin-related-anchoring protein. (1727 aa)    
Predicted Functional Partners:
Trim54
Tripartite motif-containing protein 54; May bind and stabilize microtubules during myotubes formation.
   
 
 0.723
Ttn
Uncharacterized protein.
   
 
 0.700
LOC100912348
Myotilin-like.
   
  
 0.699
Xirp1
Xin actin-binding repeat containing 1.
   
 
 0.681
LOC100909761
Myotilin-like.
   
  
 0.679
Tcap
Uncharacterized protein.
   
  
 0.673
Myoz2
Myozenin 2 (Predicted), isoform CRA_a.
   
  
 0.672
Csrp3
Cysteine and glycine-rich protein 3; Positive regulator of myogenesis. Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6. Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. I [...]
   
 
0.670
Neb
Nebulin.
   
  
0.641
Actn2
Actinin alpha 2.
   
 
 0.633
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: medium (56%) [HD]