node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cbx1 | Cbx3 | ENSRNOP00000011665 | ENSRNOP00000015828 | RCG35120, isoform CRA_a. | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | 0.547 |
Cbx1 | Cbx5 | ENSRNOP00000011665 | ENSRNOP00000073453 | RCG35120, isoform CRA_a. | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | 0.691 |
Cbx1 | Dnmt1 | ENSRNOP00000011665 | ENSRNOP00000063831 | RCG35120, isoform CRA_a. | DNA (cytosine-5)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In a [...] | 0.624 |
Cbx1 | Hdac1l | ENSRNOP00000011665 | ENSRNOP00000018423 | RCG35120, isoform CRA_a. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.672 |
Cbx1 | Setdb1 | ENSRNOP00000011665 | ENSRNOP00000073356 | RCG35120, isoform CRA_a. | SET domain bifurcated histone lysine methyltransferase 1. | 0.670 |
Cbx1 | Trim28 | ENSRNOP00000011665 | ENSRNOP00000031061 | RCG35120, isoform CRA_a. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.890 |
Cbx3 | Cbx1 | ENSRNOP00000015828 | ENSRNOP00000011665 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | RCG35120, isoform CRA_a. | 0.547 |
Cbx3 | Cbx5 | ENSRNOP00000015828 | ENSRNOP00000073453 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | 0.705 |
Cbx3 | Dnmt1 | ENSRNOP00000015828 | ENSRNOP00000063831 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | DNA (cytosine-5)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In a [...] | 0.647 |
Cbx3 | Hdac1l | ENSRNOP00000015828 | ENSRNOP00000018423 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.640 |
Cbx3 | Setdb1 | ENSRNOP00000015828 | ENSRNOP00000073356 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | SET domain bifurcated histone lysine methyltransferase 1. | 0.729 |
Cbx3 | Trim28 | ENSRNOP00000015828 | ENSRNOP00000031061 | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.905 |
Cbx5 | Cbx1 | ENSRNOP00000073453 | ENSRNOP00000011665 | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | RCG35120, isoform CRA_a. | 0.691 |
Cbx5 | Cbx3 | ENSRNOP00000073453 | ENSRNOP00000015828 | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | 0.705 |
Cbx5 | Dnmt1 | ENSRNOP00000073453 | ENSRNOP00000063831 | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | DNA (cytosine-5)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In a [...] | 0.696 |
Cbx5 | Hdac1l | ENSRNOP00000073453 | ENSRNOP00000018423 | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.610 |
Cbx5 | Setdb1 | ENSRNOP00000073453 | ENSRNOP00000073356 | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | SET domain bifurcated histone lysine methyltransferase 1. | 0.885 |
Cbx5 | Trim28 | ENSRNOP00000073453 | ENSRNOP00000031061 | Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.981 |
Dnmt1 | Cbx1 | ENSRNOP00000063831 | ENSRNOP00000011665 | DNA (cytosine-5)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In a [...] | RCG35120, isoform CRA_a. | 0.624 |
Dnmt1 | Cbx3 | ENSRNOP00000063831 | ENSRNOP00000015828 | DNA (cytosine-5)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In a [...] | Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a. | 0.647 |