node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ankrd6 | Celsr1 | ENSRNOP00000061313 | ENSRNOP00000029944 | Similar to ankyrin repeat domain 6. | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.611 |
Ankrd6 | Dvl1 | ENSRNOP00000061313 | ENSRNOP00000026439 | Similar to ankyrin repeat domain 6. | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] | 0.857 |
Ankrd6 | Dvl2 | ENSRNOP00000061313 | ENSRNOP00000024348 | Similar to ankyrin repeat domain 6. | Dishevelled segment polarity protein 2. | 0.484 |
Ankrd6 | Dvl3 | ENSRNOP00000061313 | ENSRNOP00000002323 | Similar to ankyrin repeat domain 6. | Dishevelled segment polarity protein 3. | 0.416 |
Ankrd6 | Fzd3 | ENSRNOP00000061313 | ENSRNOP00000067360 | Similar to ankyrin repeat domain 6. | Frizzled homolog 3 (Drosophila), isoform CRA_a; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.440 |
Ankrd6 | Prickle1 | ENSRNOP00000061313 | ENSRNOP00000031476 | Similar to ankyrin repeat domain 6. | Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure (By similarity). Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor (By similarity). | 0.814 |
Ankrd6 | Vangl1 | ENSRNOP00000061313 | ENSRNOP00000022182 | Similar to ankyrin repeat domain 6. | Vang-like protein. | 0.609 |
Ankrd6 | Vangl2 | ENSRNOP00000061313 | ENSRNOP00000072619 | Similar to ankyrin repeat domain 6. | Vang-like protein 2; Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). | 0.616 |
Arhgap21 | Prickle1 | ENSRNOP00000060787 | ENSRNOP00000031476 | Rho GTPase-activating protein 21. | Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure (By similarity). Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor (By similarity). | 0.718 |
Celsr1 | Ankrd6 | ENSRNOP00000029944 | ENSRNOP00000061313 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Similar to ankyrin repeat domain 6. | 0.611 |
Celsr1 | Dvl1 | ENSRNOP00000029944 | ENSRNOP00000026439 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] | 0.662 |
Celsr1 | Dvl2 | ENSRNOP00000029944 | ENSRNOP00000024348 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Dishevelled segment polarity protein 2. | 0.763 |
Celsr1 | Dvl3 | ENSRNOP00000029944 | ENSRNOP00000002323 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Dishevelled segment polarity protein 3. | 0.515 |
Celsr1 | Fzd3 | ENSRNOP00000029944 | ENSRNOP00000067360 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Frizzled homolog 3 (Drosophila), isoform CRA_a; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.789 |
Celsr1 | Fzd6 | ENSRNOP00000029944 | ENSRNOP00000006195 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Frizzled homolog 6 (Drosophila); Belongs to the G-protein coupled receptor Fz/Smo family. | 0.836 |
Celsr1 | Prickle1 | ENSRNOP00000029944 | ENSRNOP00000031476 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Prickle-like protein 1; Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure (By similarity). Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor (By similarity). | 0.797 |
Celsr1 | Vangl1 | ENSRNOP00000029944 | ENSRNOP00000022182 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Vang-like protein. | 0.871 |
Celsr1 | Vangl2 | ENSRNOP00000029944 | ENSRNOP00000072619 | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | Vang-like protein 2; Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). | 0.903 |
Dvl1 | Ankrd6 | ENSRNOP00000026439 | ENSRNOP00000061313 | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] | Similar to ankyrin repeat domain 6. | 0.857 |
Dvl1 | Celsr1 | ENSRNOP00000026439 | ENSRNOP00000029944 | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] | Cadherin, EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.662 |