STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CtnsCystinosin, lysosomal cystine transporter. (367 aa)    
Predicted Functional Partners:
Slc66a1
Lysosomal amino acid transporter 1 homolog; Amino acid transporter that specifically mediates the pH- dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes; Belongs to the laat-1 family.
   
 
 0.862
Shpk
Carbohydrate kinase-like, isoform CRA_b.
   
  
 0.815
Cln3
Battenin.
   
  
 0.624
Btg3
Protein BTG3; Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.
      
 0.579
Ybx2
Y box-binding protein 2.
      
 0.563
Corin
Atrial natriuretic peptide-converting enzyme, activated protease fragment; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB [...]
   
  
 0.559
Bnc2
Basonuclin 2 (Predicted).
      
 0.546
Hs1bp3
HCLS1-binding protein 3.
   
    0.540
Slc24a5
Solute carrier family 24, member 5 (Predicted); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.530
Slc45a2
Solute carrier family 45, member 2 (Predicted).
      
 0.525
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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