node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cttnbp2nl | Mob4 | ENSRNOP00000019680 | ENSRNOP00000020536 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | 0.970 |
Cttnbp2nl | Pdcd10 | ENSRNOP00000019680 | ENSRNOP00000013585 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. | 0.970 |
Cttnbp2nl | Sike1 | ENSRNOP00000019680 | ENSRNOP00000024270 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity). | 0.682 |
Cttnbp2nl | Stk24 | ENSRNOP00000019680 | ENSRNOP00000031981 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr [...] | 0.975 |
Cttnbp2nl | Stk25 | ENSRNOP00000019680 | ENSRNOP00000024487 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a. | 0.950 |
Cttnbp2nl | Stk26 | ENSRNOP00000019680 | ENSRNOP00000010596 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Serine/threonine kinase 26. | 0.966 |
Cttnbp2nl | Strip1 | ENSRNOP00000019680 | ENSRNOP00000025036 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin-interacting protein 1. | 0.987 |
Cttnbp2nl | Strip2 | ENSRNOP00000019680 | ENSRNOP00000068545 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin interacting protein 2. | 0.958 |
Cttnbp2nl | Strn | ENSRNOP00000019680 | ENSRNOP00000006527 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.980 |
Cttnbp2nl | Strn3 | ENSRNOP00000019680 | ENSRNOP00000074395 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity); Belongs to the WD repeat striatin family. | 0.990 |
Mob4 | Cttnbp2nl | ENSRNOP00000020536 | ENSRNOP00000019680 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | 0.970 |
Mob4 | Pdcd10 | ENSRNOP00000020536 | ENSRNOP00000013585 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. | 0.959 |
Mob4 | Sike1 | ENSRNOP00000020536 | ENSRNOP00000024270 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity). | 0.879 |
Mob4 | Stk24 | ENSRNOP00000020536 | ENSRNOP00000031981 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr [...] | 0.964 |
Mob4 | Stk25 | ENSRNOP00000020536 | ENSRNOP00000024487 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a. | 0.961 |
Mob4 | Stk26 | ENSRNOP00000020536 | ENSRNOP00000010596 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Serine/threonine kinase 26. | 0.987 |
Mob4 | Strip1 | ENSRNOP00000020536 | ENSRNOP00000025036 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Striatin-interacting protein 1. | 0.984 |
Mob4 | Strip2 | ENSRNOP00000020536 | ENSRNOP00000068545 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Striatin interacting protein 2. | 0.973 |
Mob4 | Strn | ENSRNOP00000020536 | ENSRNOP00000006527 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Striatin; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.989 |
Mob4 | Strn3 | ENSRNOP00000020536 | ENSRNOP00000074395 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity); Belongs to the WD repeat striatin family. | 0.948 |