node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Casp6 | Casp9 | ENSRNOP00000013049 | ENSRNOP00000017972 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | 0.950 |
Casp6 | Gpaa1 | ENSRNOP00000013049 | ENSRNOP00000050220 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | 0.720 |
Casp6 | LOC100912380 | ENSRNOP00000013049 | ENSRNOP00000064489 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | 0.738 |
Casp6 | Pigk | ENSRNOP00000013049 | ENSRNOP00000014725 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. | 0.723 |
Casp6 | Pigs | ENSRNOP00000013049 | ENSRNOP00000015207 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | GPI transamidase component PIG-S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity); Belongs to the PIGS family. | 0.721 |
Casp6 | Pigt | ENSRNOP00000013049 | ENSRNOP00000019761 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | Phosphatidylinositol glycan anchor biosynthesis, class T. | 0.720 |
Casp6 | Pigu | ENSRNOP00000013049 | ENSRNOP00000032963 | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | Phosphatidylinositol glycan anchor biosynthesis class U protein; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI. | 0.721 |
Casp9 | Casp6 | ENSRNOP00000017972 | ENSRNOP00000013049 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | 0.950 |
Casp9 | Gpaa1 | ENSRNOP00000017972 | ENSRNOP00000050220 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | 0.720 |
Casp9 | LOC100912380 | ENSRNOP00000017972 | ENSRNOP00000064489 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | 0.743 |
Casp9 | Pigk | ENSRNOP00000017972 | ENSRNOP00000014725 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. | 0.722 |
Casp9 | Pigs | ENSRNOP00000017972 | ENSRNOP00000015207 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | GPI transamidase component PIG-S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity); Belongs to the PIGS family. | 0.724 |
Casp9 | Pigt | ENSRNOP00000017972 | ENSRNOP00000019761 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | Phosphatidylinositol glycan anchor biosynthesis, class T. | 0.720 |
Casp9 | Pigu | ENSRNOP00000017972 | ENSRNOP00000032963 | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | Phosphatidylinositol glycan anchor biosynthesis class U protein; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI. | 0.723 |
Gpaa1 | Casp6 | ENSRNOP00000050220 | ENSRNOP00000013049 | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | Caspase-6 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity); Belongs to the peptidase C14A family. | 0.720 |
Gpaa1 | Casp9 | ENSRNOP00000050220 | ENSRNOP00000017972 | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | Caspase 9, isoform CRA_a; Belongs to the peptidase C14A family. | 0.720 |
Gpaa1 | LOC100912380 | ENSRNOP00000050220 | ENSRNOP00000064489 | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | 0.726 |
Gpaa1 | Pgap1 | ENSRNOP00000050220 | ENSRNOP00000017967 | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. | 0.969 |
Gpaa1 | Pigf | ENSRNOP00000050220 | ENSRNOP00000020600 | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | Phosphatidylinositol glycan anchor biosynthesis, class F. | 0.919 |
Gpaa1 | Pigk | ENSRNOP00000050220 | ENSRNOP00000014725 | Glycosylphosphatidylinositol anchor attachment protein 1 homolog (Yeast). | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. | 0.999 |