node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Drosha | Fus | ENSRNOP00000050633 | ENSRNOP00000033029 | Drosha ribonuclease III. | Fusion, derived from t(1216) malignant liposarcoma (Human). | 0.981 |
Drosha | Hnrnpa1 | ENSRNOP00000050633 | ENSRNOP00000052160 | Drosha ribonuclease III. | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | 0.866 |
Drosha | Hnrnpa2b1 | ENSRNOP00000050633 | ENSRNOP00000015152 | Drosha ribonuclease III. | Heterogeneous nuclear ribonucleoproteins A2/B1; Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs. Forms hnRNP particles with at least 20 other different hnRNP and he [...] | 0.579 |
Drosha | Tardbp | ENSRNOP00000050633 | ENSRNOP00000041889 | Drosha ribonuclease III. | RCG31562, isoform CRA_c. | 0.980 |
Drosha | Ybx1 | ENSRNOP00000050633 | ENSRNOP00000015875 | Drosha ribonuclease III. | Y-box-binding protein 1; DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing, DNA repair and transcription regulation. Predominantly acts as a RNA- binding protein: binds preferentially to the 5'-[CU]CUGCG-3' RNA motif and specifically recognizes mRNA transcripts modified by C5- methylcytosine (m5C). Promotes mRNA stabilization: acts by binding to m5C-containing mRNAs and recruiting the mRNA stability maintainer ELAVL1, thereby preventing mRNA decay. Component of the CRD-mediated complex that promotes MYC mRNA s [...] | 0.428 |
Fus | Drosha | ENSRNOP00000033029 | ENSRNOP00000050633 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Drosha ribonuclease III. | 0.981 |
Fus | Hnrnpa1 | ENSRNOP00000033029 | ENSRNOP00000052160 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | 0.847 |
Fus | Hnrnpa2b1 | ENSRNOP00000033029 | ENSRNOP00000015152 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Heterogeneous nuclear ribonucleoproteins A2/B1; Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs. Forms hnRNP particles with at least 20 other different hnRNP and he [...] | 0.845 |
Fus | Hnrnpd | ENSRNOP00000033029 | ENSRNOP00000046491 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Heterogeneous nuclear ribonucleoprotein D0; Binds with high affinity to RNA molecules that contain AU- rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-st [...] | 0.819 |
Fus | Sod1 | ENSRNOP00000033029 | ENSRNOP00000002885 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.910 |
Fus | Srsf2 | ENSRNOP00000033029 | ENSRNOP00000059012 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment (By similarity). | 0.880 |
Fus | Tardbp | ENSRNOP00000033029 | ENSRNOP00000041889 | Fusion, derived from t(1216) malignant liposarcoma (Human). | RCG31562, isoform CRA_c. | 0.992 |
Fus | Tnpo1 | ENSRNOP00000033029 | ENSRNOP00000020543 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Transportin 1. | 0.928 |
Fus | Ubqln2 | ENSRNOP00000033029 | ENSRNOP00000026214 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Ubiquilin 2 (Predicted). | 0.887 |
Fus | Ybx1 | ENSRNOP00000033029 | ENSRNOP00000015875 | Fusion, derived from t(1216) malignant liposarcoma (Human). | Y-box-binding protein 1; DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing, DNA repair and transcription regulation. Predominantly acts as a RNA- binding protein: binds preferentially to the 5'-[CU]CUGCG-3' RNA motif and specifically recognizes mRNA transcripts modified by C5- methylcytosine (m5C). Promotes mRNA stabilization: acts by binding to m5C-containing mRNAs and recruiting the mRNA stability maintainer ELAVL1, thereby preventing mRNA decay. Component of the CRD-mediated complex that promotes MYC mRNA s [...] | 0.829 |
Hnrnpa1 | Drosha | ENSRNOP00000052160 | ENSRNOP00000050633 | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | Drosha ribonuclease III. | 0.866 |
Hnrnpa1 | Fus | ENSRNOP00000052160 | ENSRNOP00000033029 | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | Fusion, derived from t(1216) malignant liposarcoma (Human). | 0.847 |
Hnrnpa1 | Hnrnpa2b1 | ENSRNOP00000052160 | ENSRNOP00000015152 | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | Heterogeneous nuclear ribonucleoproteins A2/B1; Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles. The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting. Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs. Forms hnRNP particles with at least 20 other different hnRNP and he [...] | 0.975 |
Hnrnpa1 | Hnrnpd | ENSRNOP00000052160 | ENSRNOP00000046491 | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | Heterogeneous nuclear ribonucleoprotein D0; Binds with high affinity to RNA molecules that contain AU- rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-st [...] | 0.677 |
Hnrnpa1 | Sod1 | ENSRNOP00000052160 | ENSRNOP00000002885 | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity). May bind to specific miRNA hairpins (By similarity). | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.462 |