node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bivm | Ercc2 | ENSRNOP00000033781 | ENSRNOP00000024247 | Basic, immunoglobulin-like variable motif-containing. | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.822 |
Bivm | Ercc3 | ENSRNOP00000033781 | ENSRNOP00000018422 | Basic, immunoglobulin-like variable motif-containing. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | 0.824 |
Bivm | Ercc5 | ENSRNOP00000033781 | ENSRNOP00000056107 | Basic, immunoglobulin-like variable motif-containing. | ERCC excision repair 5, endonuclease. | 0.812 |
Bivm | Ercc6 | ENSRNOP00000033781 | ENSRNOP00000068845 | Basic, immunoglobulin-like variable motif-containing. | ERCC excision repair 6, chromatin-remodeling factor. | 0.803 |
Bivm | Fancm | ENSRNOP00000033781 | ENSRNOP00000074177 | Basic, immunoglobulin-like variable motif-containing. | FA complementation group M. | 0.687 |
Bivm | Gtf2h1 | ENSRNOP00000033781 | ENSRNOP00000069965 | Basic, immunoglobulin-like variable motif-containing. | General transcription factor IIH subunit 1. | 0.818 |
Bivm | Hist1h2ak | ENSRNOP00000033781 | ENSRNOP00000070475 | Basic, immunoglobulin-like variable motif-containing. | Histone H2A; Belongs to the histone H2A family. | 0.723 |
Bivm | Mus81 | ENSRNOP00000033781 | ENSRNOP00000028015 | Basic, immunoglobulin-like variable motif-containing. | Crossover junction endonuclease MUS81; Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity); Belongs to the XPF family. | 0.768 |
Bivm | Pcna | ENSRNOP00000033781 | ENSRNOP00000028887 | Basic, immunoglobulin-like variable motif-containing. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.805 |
Bivm | Wrn | ENSRNOP00000033781 | ENSRNOP00000055596 | Basic, immunoglobulin-like variable motif-containing. | WRN RecQ-like helicase. | 0.856 |
Ercc2 | Bivm | ENSRNOP00000024247 | ENSRNOP00000033781 | ERCC excision repair 2, TFIIH core complex helicase subunit. | Basic, immunoglobulin-like variable motif-containing. | 0.822 |
Ercc2 | Ercc3 | ENSRNOP00000024247 | ENSRNOP00000018422 | ERCC excision repair 2, TFIIH core complex helicase subunit. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | 0.999 |
Ercc2 | Ercc5 | ENSRNOP00000024247 | ENSRNOP00000056107 | ERCC excision repair 2, TFIIH core complex helicase subunit. | ERCC excision repair 5, endonuclease. | 0.966 |
Ercc2 | Ercc6 | ENSRNOP00000024247 | ENSRNOP00000068845 | ERCC excision repair 2, TFIIH core complex helicase subunit. | ERCC excision repair 6, chromatin-remodeling factor. | 0.884 |
Ercc2 | Fancm | ENSRNOP00000024247 | ENSRNOP00000074177 | ERCC excision repair 2, TFIIH core complex helicase subunit. | FA complementation group M. | 0.611 |
Ercc2 | Gtf2h1 | ENSRNOP00000024247 | ENSRNOP00000069965 | ERCC excision repair 2, TFIIH core complex helicase subunit. | General transcription factor IIH subunit 1. | 0.997 |
Ercc2 | Wrn | ENSRNOP00000024247 | ENSRNOP00000055596 | ERCC excision repair 2, TFIIH core complex helicase subunit. | WRN RecQ-like helicase. | 0.687 |
Ercc3 | Bivm | ENSRNOP00000018422 | ENSRNOP00000033781 | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | Basic, immunoglobulin-like variable motif-containing. | 0.824 |
Ercc3 | Ercc2 | ENSRNOP00000018422 | ENSRNOP00000024247 | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | ERCC excision repair 2, TFIIH core complex helicase subunit. | 0.999 |
Ercc3 | Ercc5 | ENSRNOP00000018422 | ENSRNOP00000056107 | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | ERCC excision repair 5, endonuclease. | 0.968 |