STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem98Transmembrane protein 98; Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1). (226 aa)    
Predicted Functional Partners:
Prss56
Serine protease 56; Belongs to the peptidase S1 family.
      
 0.850
Myrf
Myelin regulatory factor.
   
  
 0.702
Mfrp
Membrane frizzled-related protein.
   
  
 0.606
Scara3
Scavenger receptor class A, member 3 (Predicted).
      
 0.571
Ppp1r32
Protein phosphatase 1 regulatory subunit 32.
      
 0.528
Tmem176a
Transmembrane protein 176A.
   
  
 0.523
Sel1l3
SEL1L family member 3.
      
 0.505
Cisd3
CDGSH iron sulfur domain 3.
   
  
 0.503
Slc25a41
Similar to solute carrier family 25 member 25; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.497
Ccdc9
Coiled-coil domain-containing 9.
      
 0.487
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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