node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bhlhe22 | Fezf2 | ENSRNOP00000038593 | ENSRNOP00000012452 | Basic helix-loop-helix family, member e22. | Zinc finger protein 312 (Predicted). | 0.575 |
Bhlhe22 | Grpr | ENSRNOP00000038593 | ENSRNOP00000005559 | Basic helix-loop-helix family, member e22. | Gastrin-releasing peptide receptor; Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory; Belon [...] | 0.676 |
Bhlhe22 | Pax2 | ENSRNOP00000038593 | ENSRNOP00000040130 | Basic helix-loop-helix family, member e22. | Paired box gene 2 (Predicted). | 0.556 |
Bhlhe22 | Pax6 | ENSRNOP00000038593 | ENSRNOP00000071013 | Basic helix-loop-helix family, member e22. | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | 0.628 |
Bhlhe22 | Prdm8 | ENSRNOP00000038593 | ENSRNOP00000002746 | Basic helix-loop-helix family, member e22. | PR/SET domain 8. | 0.849 |
Bhlhe22 | Ptf1a | ENSRNOP00000038593 | ENSRNOP00000022727 | Basic helix-loop-helix family, member e22. | Pancreas transcription factor 1 subunit alpha; Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an impor [...] | 0.589 |
Bhlhe22 | Slc17a6 | ENSRNOP00000038593 | ENSRNOP00000022383 | Basic helix-loop-helix family, member e22. | Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. | 0.574 |
Bhlhe22 | Tbr1 | ENSRNOP00000038593 | ENSRNOP00000059530 | Basic helix-loop-helix family, member e22. | T-box brain transcription factor 1. | 0.598 |
Bhlhe22 | Vsx1 | ENSRNOP00000038593 | ENSRNOP00000058189 | Basic helix-loop-helix family, member e22. | Visual system homeobox 1. | 0.584 |
Bhlhe22 | Vsx2 | ENSRNOP00000038593 | ENSRNOP00000015889 | Basic helix-loop-helix family, member e22. | Ceh-10 homeo domain containing homolog (C. elegans), isoform CRA_a. | 0.580 |
Fezf2 | Bhlhe22 | ENSRNOP00000012452 | ENSRNOP00000038593 | Zinc finger protein 312 (Predicted). | Basic helix-loop-helix family, member e22. | 0.575 |
Fezf2 | Pax6 | ENSRNOP00000012452 | ENSRNOP00000071013 | Zinc finger protein 312 (Predicted). | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | 0.682 |
Fezf2 | Tbr1 | ENSRNOP00000012452 | ENSRNOP00000059530 | Zinc finger protein 312 (Predicted). | T-box brain transcription factor 1. | 0.865 |
Grpr | Bhlhe22 | ENSRNOP00000005559 | ENSRNOP00000038593 | Gastrin-releasing peptide receptor; Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory; Belon [...] | Basic helix-loop-helix family, member e22. | 0.676 |
Grpr | Slc17a6 | ENSRNOP00000005559 | ENSRNOP00000022383 | Gastrin-releasing peptide receptor; Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory; Belon [...] | Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. | 0.543 |
Pax2 | Bhlhe22 | ENSRNOP00000040130 | ENSRNOP00000038593 | Paired box gene 2 (Predicted). | Basic helix-loop-helix family, member e22. | 0.556 |
Pax2 | Pax6 | ENSRNOP00000040130 | ENSRNOP00000071013 | Paired box gene 2 (Predicted). | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters (By similarity). Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains; Belongs to the paired homeobox family. | 0.515 |
Pax2 | Ptf1a | ENSRNOP00000040130 | ENSRNOP00000022727 | Paired box gene 2 (Predicted). | Pancreas transcription factor 1 subunit alpha; Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an impor [...] | 0.602 |
Pax2 | Slc17a6 | ENSRNOP00000040130 | ENSRNOP00000022383 | Paired box gene 2 (Predicted). | Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. | 0.467 |
Pax2 | Vsx2 | ENSRNOP00000040130 | ENSRNOP00000015889 | Paired box gene 2 (Predicted). | Ceh-10 homeo domain containing homolog (C. elegans), isoform CRA_a. | 0.588 |