STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc39a11Solute carrier family 39 (zinc transporter), member 11; Zinc transporter ZIP11; Functions as a cellular zinc transporter (335 aa)    
Predicted Functional Partners:
Slc39a9
Solute carrier family 39 (zinc transporter), member 9; Zinc transporter ZIP9; May act as a zinc-influx transporter
    
 
 0.898
Slc39a4
Solute carrier family 39 (zinc transporter), member 4; Zinc transporter ZIP4; Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity)
   
 
 0.847
Slc30a7
Solute carrier family 30 (zinc transporter), member 5/7; Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)
   
 
 0.827
Slc30a9
Solute carrier family 30 (zinc transporter), member 9
  
  
 0.801
Slc30a1
Solute carrier family 30 (zinc transporter), member 1; Zinc transporter 1; May be involved in zinc transport out of the cell
  
 
 0.800
Slc30a2
Solute carrier family 30 (zinc transporter), member 2; Involved in accumulation of zinc in endosomal/lysosomal vesicles
   
 
 0.789
Slc39a13
Solute carrier family 39 (zinc transporter), member 13; Zinc transporter ZIP13; Acts as a zinc-influx transporter
      
 0.788
Slc39a6
Solute carrier family 39 (zinc transporter), member 6; Zinc transporter ZIP6; May act as a zinc-influx transporter
   
 
 0.782
Slc39a8
Solute carrier family 39 (zinc transporter), member 8; Zinc transporter ZIP8; Acts as a manganese and zinc influx transporter. Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain
   
 
 0.751
Slc30a4
Solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, may be by sequestration into an intracellular compartment
   
 
 0.737
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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