STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3f3bH3 histone family member 3A. (136 aa)    
Predicted Functional Partners:
Cbx5
Chromobox homolog 5 (Drosophila HP1a) (Predicted), isoform CRA_a.
   
 
 0.960
Rag2
Recombination-activating 2.
    
 
 0.899
Atrx
Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...]
    
 
 0.857
Cenpa
Similar to centromere protein A (Predicted), isoform CRA_b.
  
0.848
Ash1l
ASH1-like histone lysine methyltransferase.
   
 
 0.812
Zmynd11
Zinc finger, MYND-type-containing 11.
   
 
 0.797
Ing5
Inhibitor of growth protein.
   
 
 0.795
Dpf3
Double PHD fingers 3.
    
 
 0.793
Cbx1
RCG35120, isoform CRA_a.
   
 
 0.784
Trim66
Tripartite motif-containing 66.
    
   0.783
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.