STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hba-a1Hemoglobin alpha, adult chain 3; Belongs to the globin family. (142 aa)    
Predicted Functional Partners:
Hbb
Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family.
  
0.983
Hbe1
Hemoglobin subunit epsilon 1; Belongs to the globin family.
  
0.963
Hbg1
Hemoglobin subunit gamma 1; Belongs to the globin family.
  
0.963
Hp
Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...]
   
 0.962
Hba-a2
Hemoglobin alpha, adult chain 2; Belongs to the globin family.
  
 
 
0.910
LOC103694855
Hemoglobin subunit beta-2-like; Belongs to the globin family.
  
0.902
Hbb-b1
Beta globin minor gene; Belongs to the globin family.
  
0.896
LOC103694857
Hemoglobin subunit beta-2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family.
  
0.894
LOC100134871
Beta globin minor gene.
  
0.891
Hbe2
Hemoglobin, epsilon 2; Belongs to the globin family.
  
0.855
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.