STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmprss7Transmembrane protease serine 7; Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position; Belongs to the peptidase S1 family. (829 aa)    
Predicted Functional Partners:
Serpinc1
Serine (Or cysteine) peptidase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.
   
 
 0.719
Serpina1
Alpha-1-antiproteinase; Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin; Belongs to the serpin family.
    
 
 0.663
Serpinf2
Serpin family F member 2; Belongs to the serpin family.
   
 
 0.589
Serpina5
Serine (Or cysteine) peptidase inhibitor, clade A, member 5; Belongs to the serpin family.
    
 
 0.485
Spint2
Serine peptidase inhibitor, Kunitz type, 2.
   
 
 0.466
Serpinf1
Serine (Or cysteine) peptidase inhibitor, clade F, member 1, isoform CRA_c; Belongs to the serpin family.
    
 
 0.456
Hjv
Hemojuvelin; Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis. Belongs to the repulsive guidance molecule (RGM) family.
    
 
 0.442
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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