node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bhlhe23 | Lrp2bp | ENSRNOP00000013690 | ENSRNOP00000041732 | Similar to basic helix-loop-helix transcriptional regulator beta4 (Predicted). | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.495 |
Bhlhe23 | Wscd2 | ENSRNOP00000013690 | ENSRNOP00000071851 | Similar to basic helix-loop-helix transcriptional regulator beta4 (Predicted). | WSC domain-containing 2. | 0.446 |
Erlec1 | Lrp2bp | ENSRNOP00000043115 | ENSRNOP00000041732 | Endoplasmic reticulum lectin 1. | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.615 |
Erlec1 | Os9 | ENSRNOP00000043115 | ENSRNOP00000044914 | Endoplasmic reticulum lectin 1. | Protein OS-9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 (By similarity). | 0.776 |
Lrit3 | Lrp2bp | ENSRNOP00000076143 | ENSRNOP00000041732 | Leucine-rich repeat, Ig-like and transmembrane domains 3. | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.646 |
Lrit3 | Slco5a1 | ENSRNOP00000076143 | ENSRNOP00000011940 | Leucine-rich repeat, Ig-like and transmembrane domains 3. | Solute carrier organic anion transporter family member. | 0.472 |
Lrp2 | Lrp2bp | ENSRNOP00000075159 | ENSRNOP00000041732 | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium. Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated r [...] | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.512 |
Lrp2bp | Bhlhe23 | ENSRNOP00000041732 | ENSRNOP00000013690 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Similar to basic helix-loop-helix transcriptional regulator beta4 (Predicted). | 0.495 |
Lrp2bp | Erlec1 | ENSRNOP00000041732 | ENSRNOP00000043115 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Endoplasmic reticulum lectin 1. | 0.615 |
Lrp2bp | Lrit3 | ENSRNOP00000041732 | ENSRNOP00000076143 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Leucine-rich repeat, Ig-like and transmembrane domains 3. | 0.646 |
Lrp2bp | Lrp2 | ENSRNOP00000041732 | ENSRNOP00000075159 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium. Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated r [...] | 0.512 |
Lrp2bp | Marchf3 | ENSRNOP00000041732 | ENSRNOP00000030051 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.577 |
Lrp2bp | Myo9a | ENSRNOP00000041732 | ENSRNOP00000015963 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Unconventional myosin-IXa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity). | 0.521 |
Lrp2bp | Os9 | ENSRNOP00000041732 | ENSRNOP00000044914 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Protein OS-9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 (By similarity). | 0.615 |
Lrp2bp | Prpsap1 | ENSRNOP00000041732 | ENSRNOP00000013573 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Phosphoribosyl pyrophosphate synthase-associated protein 1; Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. | 0.669 |
Lrp2bp | Slco5a1 | ENSRNOP00000041732 | ENSRNOP00000011940 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | Solute carrier organic anion transporter family member. | 0.499 |
Lrp2bp | Wscd2 | ENSRNOP00000041732 | ENSRNOP00000071851 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | WSC domain-containing 2. | 0.646 |
Marchf3 | Lrp2bp | ENSRNOP00000030051 | ENSRNOP00000041732 | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.577 |
Marchf3 | Prpsap1 | ENSRNOP00000030051 | ENSRNOP00000013573 | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | Phosphoribosyl pyrophosphate synthase-associated protein 1; Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. | 0.500 |
Myo9a | Lrp2bp | ENSRNOP00000015963 | ENSRNOP00000041732 | Unconventional myosin-IXa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity). | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.521 |