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Man2c1 protein (Rattus norvegicus) - STRING interaction network
"Man2c1" - Alpha-mannosidase 2C1 in Rattus norvegicus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Man2c1Alpha-mannosidase 2C1 (1039 aa)    
Predicted Functional Partners:
Man2b1
Lysosomal alpha-mannosidase precursor (1009 aa)
     
 
  0.949
Man2b2
Epididymis-specific alpha-mannosidase precursor (981 aa)
     
 
  0.909
Xrn1
Protein Xrn1 (1723 aa)
     
      0.662
Engase
Cytosolic endo-beta-N-acetylglucosaminidase (732 aa)
   
   
  0.654
Exosc6
Protein Exosc6 (272 aa)
       
      0.631
Man2a2
Alpha-mannosidase 2x (1161 aa)
     
   
  0.525
Snupn
Snurportin-1 ; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs (By similarity) (358 aa)
           
  0.509
Snapap
SNARE-associated protein Snapin ; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulat [...] (136 aa)
       
      0.489
Nsun2
tRNA (cytosine-5-)-methyltransferase NSUN2 (782 aa)
           
  0.485
Echs1
Short-chain enoyl-CoA hydratase; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate (290 aa)
           
  0.453
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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