Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Sialate O-acetylesterase; Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid (542 aa)
Predicted Functional Partners:
Epididymal-specific lipocalin ELP16; Lipocalin 6; Belongs to the calycin superfamily. Lipocalin family (181 aa)
Sialic acid binding Ig-like lectin 10 (372 aa)
CD22 antigen (Predicted); CD22 molecule (852 aa)
Transmembrane protein 242; Similar to 5730437N04Rik protein (140 aa)
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) (2278 aa)
CAS1 domain containing 1 (742 aa)
Sialic acid binding Ig-like lectin 15 (327 aa)
N-acylethanolamine-hydrolyzing acid amidase; Degrades bioactive fatty acid amides to their corresponding acids, with the following preference- N- palmitoylethanolamine > N-myristoylethanolamine > N- stearoylethanolamine > N-oleoylethanolamine > N- linoleoylethanolamine > N-arachidonoylethanolamine (362 aa)
Diphthamide biosynthesis 3 (82 aa)
V-set and immunoglobulin domain containing 2 (328 aa)
Your Current Organism:
NCBI taxonomy Id: 10116 Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats