STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sohlh1Spermatogenesis and oogenesis-specific basic helix-loop-helix 1. (357 aa)    
Predicted Functional Partners:
Stra8
Stimulated by retinoic acid 8.
      
 0.841
Nobox
Similar to newborn ovary homeodomain protein (Predicted).
      
 0.820
Figla
Folliculogenesis-specific bHLH transcription factor.
   
  
 0.819
Lhx8
LIM homeobox 8.
      
 0.811
Sohlh2
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; Probable transcription factor, which may be involved in spermatogenesis and oogenesis.
   
  
0.767
Zbtb16
Promyelocytic leukemia zinc finger protein.
      
 0.747
Nanos2
Nanos C2HC-type zinc finger 2; Belongs to the nanos family.
      
 0.715
Bcl6b
BCL6B, transcription repressor.
      
 0.715
Gfra1
GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor; Belongs to the GDNFR family.
      
 0.710
Dmrt1
Doublesex and mab-3 related transcription factor 1.
   
  
 0.669
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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