node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apoe | App | ENSRNOP00000071702 | ENSRNOP00000041613 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.994 |
Apoe | Hbg1 | ENSRNOP00000071702 | ENSRNOP00000043418 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Hemoglobin subunit gamma 1; Belongs to the globin family. | 0.781 |
App | Apoe | ENSRNOP00000041613 | ENSRNOP00000071702 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.994 |
App | Hbg1 | ENSRNOP00000041613 | ENSRNOP00000043418 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Hemoglobin subunit gamma 1; Belongs to the globin family. | 0.696 |
Hba-a1 | Hba-a2 | ENSRNOP00000041451 | ENSRNOP00000044081 | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | 0.910 |
Hba-a1 | Hba1 | ENSRNOP00000041451 | ENSRNOP00000044233 | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | Hemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | 0.691 |
Hba-a1 | Hbb | ENSRNOP00000041451 | ENSRNOP00000070324 | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | 0.983 |
Hba-a1 | Hbe1 | ENSRNOP00000041451 | ENSRNOP00000040010 | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | Hemoglobin subunit epsilon 1; Belongs to the globin family. | 0.963 |
Hba-a1 | Hbg1 | ENSRNOP00000041451 | ENSRNOP00000043418 | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | Hemoglobin subunit gamma 1; Belongs to the globin family. | 0.963 |
Hba-a1 | Hbz | ENSRNOP00000041451 | ENSRNOP00000027851 | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | Hemoglobin subunit zeta; Belongs to the globin family. | 0.613 |
Hba-a2 | Hba-a1 | ENSRNOP00000044081 | ENSRNOP00000041451 | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | 0.910 |
Hba-a2 | Hba1 | ENSRNOP00000044081 | ENSRNOP00000044233 | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | Hemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | 0.740 |
Hba-a2 | Hbb | ENSRNOP00000044081 | ENSRNOP00000070324 | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | 0.954 |
Hba-a2 | Hbe1 | ENSRNOP00000044081 | ENSRNOP00000040010 | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | Hemoglobin subunit epsilon 1; Belongs to the globin family. | 0.961 |
Hba-a2 | Hbg1 | ENSRNOP00000044081 | ENSRNOP00000043418 | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | Hemoglobin subunit gamma 1; Belongs to the globin family. | 0.961 |
Hba-a2 | Hbz | ENSRNOP00000044081 | ENSRNOP00000027851 | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | Hemoglobin subunit zeta; Belongs to the globin family. | 0.546 |
Hba1 | Hba-a1 | ENSRNOP00000044233 | ENSRNOP00000041451 | Hemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | Hemoglobin alpha, adult chain 3; Belongs to the globin family. | 0.691 |
Hba1 | Hba-a2 | ENSRNOP00000044233 | ENSRNOP00000044081 | Hemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | Hemoglobin alpha, adult chain 2; Belongs to the globin family. | 0.740 |
Hba1 | Hbb | ENSRNOP00000044233 | ENSRNOP00000070324 | Hemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | 0.991 |
Hba1 | Hbe1 | ENSRNOP00000044233 | ENSRNOP00000040010 | Hemoglobin subunit alpha-1/2; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. | Hemoglobin subunit epsilon 1; Belongs to the globin family. | 0.889 |