node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Chuk | Gpr83 | ENSRNOP00000034134 | ENSRNOP00000043707 | Component of inhibitor of nuclear factor kappa B kinase complex. | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | 0.900 |
Chuk | Ikbkb | ENSRNOP00000034134 | ENSRNOP00000025851 | Component of inhibitor of nuclear factor kappa B kinase complex. | Inhibitor of nuclear factor kappa-B kinase subunit beta; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is transloca [...] | 0.999 |
Chuk | Irs1 | ENSRNOP00000034134 | ENSRNOP00000019579 | Component of inhibitor of nuclear factor kappa B kinase complex. | Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. | 0.926 |
Chuk | Irs2 | ENSRNOP00000034134 | ENSRNOP00000036862 | Component of inhibitor of nuclear factor kappa B kinase complex. | Insulin receptor substrate 2. | 0.914 |
Chuk | Irs3 | ENSRNOP00000034134 | ENSRNOP00000001874 | Component of inhibitor of nuclear factor kappa B kinase complex. | Insulin receptor substrate 3, isoform CRA_a. | 0.908 |
Chuk | Pgr15l | ENSRNOP00000034134 | ENSRNOP00000034633 | Component of inhibitor of nuclear factor kappa B kinase complex. | Similar to G protein-coupled receptor PGR15L (Predicted); Belongs to the G-protein coupled receptor 1 family. | 0.900 |
Gpr171 | Gpr83 | ENSRNOP00000038911 | ENSRNOP00000043707 | G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | 0.746 |
Gpr83 | Chuk | ENSRNOP00000043707 | ENSRNOP00000034134 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Component of inhibitor of nuclear factor kappa B kinase complex. | 0.900 |
Gpr83 | Gpr171 | ENSRNOP00000043707 | ENSRNOP00000038911 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. | 0.746 |
Gpr83 | Ikbkb | ENSRNOP00000043707 | ENSRNOP00000025851 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Inhibitor of nuclear factor kappa-B kinase subunit beta; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is transloca [...] | 0.900 |
Gpr83 | Irs1 | ENSRNOP00000043707 | ENSRNOP00000019579 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. | 0.900 |
Gpr83 | Irs2 | ENSRNOP00000043707 | ENSRNOP00000036862 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Insulin receptor substrate 2. | 0.901 |
Gpr83 | Irs3 | ENSRNOP00000043707 | ENSRNOP00000001874 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Insulin receptor substrate 3, isoform CRA_a. | 0.900 |
Gpr83 | Npy | ENSRNOP00000043707 | ENSRNOP00000013146 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. | 0.955 |
Gpr83 | Pgr15l | ENSRNOP00000043707 | ENSRNOP00000034633 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Similar to G protein-coupled receptor PGR15L (Predicted); Belongs to the G-protein coupled receptor 1 family. | 0.906 |
Gpr83 | Ppy | ENSRNOP00000043707 | ENSRNOP00000028318 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Pancreatic prohormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | 0.900 |
Gpr83 | Pyy | ENSRNOP00000043707 | ENSRNOP00000028323 | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. | 0.913 |
Ikbkb | Chuk | ENSRNOP00000025851 | ENSRNOP00000034134 | Inhibitor of nuclear factor kappa-B kinase subunit beta; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is transloca [...] | Component of inhibitor of nuclear factor kappa B kinase complex. | 0.999 |
Ikbkb | Gpr83 | ENSRNOP00000025851 | ENSRNOP00000043707 | Inhibitor of nuclear factor kappa-B kinase subunit beta; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is transloca [...] | Glucocorticoid-induced receptor; Belongs to the G-protein coupled receptor 1 family. | 0.900 |
Ikbkb | Irs1 | ENSRNOP00000025851 | ENSRNOP00000019579 | Inhibitor of nuclear factor kappa-B kinase subunit beta; Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is transloca [...] | Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. | 0.980 |