node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cask | Epb41 | ENSRNOP00000072295 | ENSRNOP00000071712 | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | Erythrocyte membrane protein band 4.1. | 0.779 |
Cask | Epb41l3 | ENSRNOP00000072295 | ENSRNOP00000022849 | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | Erythrocyte protein band 4.1-like 3, isoform CRA_d. | 0.611 |
Cask | Epb41l5 | ENSRNOP00000072295 | ENSRNOP00000045431 | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | 0.535 |
Cask | Patj | ENSRNOP00000072295 | ENSRNOP00000010211 | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity). | 0.432 |
Ccdc163 | Epb41l5 | ENSRNOP00000053802 | ENSRNOP00000045431 | Coiled-coil domain-containing 163. | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | 0.561 |
Ccdc163 | Morc2b | ENSRNOP00000053802 | ENSRNOP00000054417 | Coiled-coil domain-containing 163. | Microrchidia 2B. | 0.695 |
Cdh1 | Epb41l5 | ENSRNOP00000027346 | ENSRNOP00000045431 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | 0.555 |
Cdh1 | Mpp5 | ENSRNOP00000027346 | ENSRNOP00000012005 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] | 0.449 |
Cdh1 | Patj | ENSRNOP00000027346 | ENSRNOP00000010211 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. | InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity). | 0.591 |
Epb41 | Cask | ENSRNOP00000071712 | ENSRNOP00000072295 | Erythrocyte membrane protein band 4.1. | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | 0.779 |
Epb41 | Epb41l3 | ENSRNOP00000071712 | ENSRNOP00000022849 | Erythrocyte membrane protein band 4.1. | Erythrocyte protein band 4.1-like 3, isoform CRA_d. | 0.596 |
Epb41 | Epb41l5 | ENSRNOP00000071712 | ENSRNOP00000045431 | Erythrocyte membrane protein band 4.1. | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | 0.670 |
Epb41l3 | Cask | ENSRNOP00000022849 | ENSRNOP00000072295 | Erythrocyte protein band 4.1-like 3, isoform CRA_d. | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | 0.611 |
Epb41l3 | Epb41 | ENSRNOP00000022849 | ENSRNOP00000071712 | Erythrocyte protein band 4.1-like 3, isoform CRA_d. | Erythrocyte membrane protein band 4.1. | 0.596 |
Epb41l3 | Epb41l5 | ENSRNOP00000022849 | ENSRNOP00000045431 | Erythrocyte protein band 4.1-like 3, isoform CRA_d. | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | 0.526 |
Epb41l5 | Cask | ENSRNOP00000045431 | ENSRNOP00000072295 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | Peripheral plasma membrane protein CASK; Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1; Belongs to the MAGUK family. | 0.535 |
Epb41l5 | Ccdc163 | ENSRNOP00000045431 | ENSRNOP00000053802 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | Coiled-coil domain-containing 163. | 0.561 |
Epb41l5 | Cdh1 | ENSRNOP00000045431 | ENSRNOP00000027346 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. | 0.555 |
Epb41l5 | Epb41 | ENSRNOP00000045431 | ENSRNOP00000071712 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | Erythrocyte membrane protein band 4.1. | 0.670 |
Epb41l5 | Epb41l3 | ENSRNOP00000045431 | ENSRNOP00000022849 | Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. | Erythrocyte protein band 4.1-like 3, isoform CRA_d. | 0.526 |