STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2afb3H2A histone family, member B3 (116 aa)    
Predicted Functional Partners:
Hist1h2bh
Histone cluster 1, h2bd-like; Similar to Histone H2B 291B
   
 0.978
Hist1h2bd
Histone cluster 1, h2bd; Belongs to the histone H2B family
   
 0.971
rCG_23123
Histone cluster 1, h2bc-like; Belongs to the histone H2B family
   
 0.971
Hist1h2bo
Histone cluster 1 h2b family member o; Belongs to the histone H2B family
   
 0.971
Hist1h2bk
Histone cluster 1 h2b family member k; Belongs to the histone H2B family
   
 0.971
Hist2h2be
Histone cluster 2, h2be; Belongs to the histone H2B family
   
 0.971
Hist3h2ba
Histone cluster 3, h2ba; Belongs to the histone H2B family
   
 0.971
Hist1h2bf
Histone cluster 1, h2bf; Belongs to the histone H2B family
   
 0.971
Hist3h2bb
Histone cluster 3 h2b family member b; Belongs to the histone H2B family
   
 0.971
Hist1h2ba
Histone cluster 1 h2b family member a; Histone H2B type 1-A; Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones th [...]
   
 0.951
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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