STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Parp14Poly [ADP-ribose] polymerase. (1787 aa)    
Predicted Functional Partners:
Dtx3l
Deltex E3 ubiquitin ligase 3L.
   
 
0.885
Parp9
Poly [ADP-ribose] polymerase.
  
 
0.840
Ifih1
Interferon-induced with helicase C domain 1.
   
 
 0.814
Parp3
Poly [ADP-ribose] polymerase.
   
 
 0.796
Parp16
Protein mono-ADP-ribosyltransferase PARP16; Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those processes. May play a role in the unfolded protein response (UPR), by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP- ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases.
      
 0.782
Rtp4
Receptor (chemosensory) transporter protein 4.
   
  
 0.780
Ifi47
Interferon gamma-inducible protein 47.
   
  
 0.753
Parp2
Poly [ADP-ribose] polymerase.
   
 
 0.753
Ifi44
Interferon-induced protein 44, isoform CRA_a.
   
  
 0.749
Rnf213
Ring finger protein 213.
   
 
 0.740
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.