STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Eif1aEukaryotic translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). (144 aa)    
Predicted Functional Partners:
D3ZGS7_RAT
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.971
Fau
Ubiquitin-like protein FUBI.
   
 
 0.971
LOC687780
Ubiquitin-like protein fubi and ribosomal protein S30-like.
   
 
 0.971
LOC687780-2
FAU, ubiquitin like and ribosomal protein S30 fusion.
   
 
 0.971
Eif2s2
Eukaryotic translation initiation factor 2, subunit 2 (Beta), isoform CRA_a.
   
 
 0.960
Mrps6
Mitochondrial ribosomal protein S6.
  
 
 0.953
Rps15
40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 
 0.944
D3ZAK6_RAT
Uncharacterized protein.
  
 
 0.944
Eif2s1
Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction catalyzed [...]
   
 
 0.943
Rps5
40S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.942
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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