node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aqr | Clec16a | ENSRNOP00000011950 | ENSRNOP00000075216 | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. | C-type lectin domain-containing 16A. | 0.701 |
Aqr | Wdr44 | ENSRNOP00000011950 | ENSRNOP00000074327 | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.793 |
Clec16a | Aqr | ENSRNOP00000075216 | ENSRNOP00000011950 | C-type lectin domain-containing 16A. | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. | 0.701 |
Clec16a | Wdr44 | ENSRNOP00000075216 | ENSRNOP00000074327 | C-type lectin domain-containing 16A. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.709 |
Fxyd3 | Rrbp1 | ENSRNOP00000028637 | ENSRNOP00000052465 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. Belongs to the FXYD family. | Ribosome-binding protein 1. | 0.402 |
Fxyd3 | Slc25a40 | ENSRNOP00000028637 | ENSRNOP00000058058 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. Belongs to the FXYD family. | Solute carrier family 25 member 40. | 0.483 |
Fxyd3 | Wdr44 | ENSRNOP00000028637 | ENSRNOP00000074327 | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. Belongs to the FXYD family. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.548 |
LOC686087 | Wdr44 | ENSRNOP00000073210 | ENSRNOP00000074327 | Similar to motile sperm domain containing 1. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.610 |
Mospd1 | Wdr44 | ENSRNOP00000003192 | ENSRNOP00000074327 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.619 |
Mospd3 | Wdr44 | ENSRNOP00000001890 | ENSRNOP00000074327 | Motile sperm domain containing 3, isoform CRA_b. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.590 |
Rrbp1 | Fxyd3 | ENSRNOP00000052465 | ENSRNOP00000028637 | Ribosome-binding protein 1. | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. Belongs to the FXYD family. | 0.402 |
Rrbp1 | Slc25a40 | ENSRNOP00000052465 | ENSRNOP00000058058 | Ribosome-binding protein 1. | Solute carrier family 25 member 40. | 0.605 |
Rrbp1 | Wdr44 | ENSRNOP00000052465 | ENSRNOP00000074327 | Ribosome-binding protein 1. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.598 |
Rwdd3 | Wdr44 | ENSRNOP00000039966 | ENSRNOP00000074327 | RWD domain-containing protein 3; Enhancer of SUMO conjugation. Via its interaction with UBE2I/UBC9, increases SUMO conjugation to proteins by promoting the binding of E1 and E2 enzymes, thioester linkage between SUMO and UBE2I/UBC9 and transfer of SUMO to specific target proteins which include HIF1A, PIAS, NFKBIA, NR3C1 and TOP1. Positively regulates the NF-kappa-B signaling pathway by enhancing the sumoylation of NF-kappa-B inhibitor alpha (NFKBIA), promoting its stabilization which consequently leads to an increased inhibition of NF-kappa-B transcriptional activity. Negatively regula [...] | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.572 |
Slc25a40 | Fxyd3 | ENSRNOP00000058058 | ENSRNOP00000028637 | Solute carrier family 25 member 40. | FXYD domain-containing ion transport regulator 3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. Belongs to the FXYD family. | 0.483 |
Slc25a40 | Rrbp1 | ENSRNOP00000058058 | ENSRNOP00000052465 | Solute carrier family 25 member 40. | Ribosome-binding protein 1. | 0.605 |
Slc25a40 | Slc6a6 | ENSRNOP00000058058 | ENSRNOP00000072080 | Solute carrier family 25 member 40. | Sodium- and chloride-dependent taurine transporter; Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake (By similarity). Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. | 0.576 |
Slc25a40 | Wdr44 | ENSRNOP00000058058 | ENSRNOP00000074327 | Solute carrier family 25 member 40. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.709 |
Slc6a6 | Slc25a40 | ENSRNOP00000072080 | ENSRNOP00000058058 | Sodium- and chloride-dependent taurine transporter; Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake (By similarity). Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. | Solute carrier family 25 member 40. | 0.576 |
Slc6a6 | Wdr44 | ENSRNOP00000072080 | ENSRNOP00000074327 | Sodium- and chloride-dependent taurine transporter; Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake (By similarity). Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. | WD repeat-containing protein 44; Downstream effector for RAB11. May be involved in vesicle recycling. | 0.575 |