node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Akr1c15 | Cyp2c12 | ENSRNOP00000055113 | ENSRNOP00000015802 | Aldo-keto reductase family 1 member C15; Catalyzes the NADPH-dependent reduction of a variety of substrates including aromatic and aliphatic aldehydes, quinones, ketones, dicarbonyl compounds and 17-ketosteroids. Catalyzes the NADP(+)-dependent oxidation of aromatic, alicyclic and aliphatic alcohols, and 17beta-hydroxysteroids. To a lesser extent, can also catalyze the reduction of some aldoses and ketoses and the oxidation of some sugar alcohols. In the stomach, lung and colon tissues, mediates the reduction of farnesal and geranylgeranial into farnesol and geranylgeraniol respectivel [...] | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | 0.660 |
Akr1c15 | Cyp2c13 | ENSRNOP00000055113 | ENSRNOP00000067531 | Aldo-keto reductase family 1 member C15; Catalyzes the NADPH-dependent reduction of a variety of substrates including aromatic and aliphatic aldehydes, quinones, ketones, dicarbonyl compounds and 17-ketosteroids. Catalyzes the NADP(+)-dependent oxidation of aromatic, alicyclic and aliphatic alcohols, and 17beta-hydroxysteroids. To a lesser extent, can also catalyze the reduction of some aldoses and ketoses and the oxidation of some sugar alcohols. In the stomach, lung and colon tissues, mediates the reduction of farnesal and geranylgeranial into farnesol and geranylgeraniol respectivel [...] | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.656 |
Akr1c15 | LOC259244-2 | ENSRNOP00000055113 | ENSRNOP00000044277 | Aldo-keto reductase family 1 member C15; Catalyzes the NADPH-dependent reduction of a variety of substrates including aromatic and aliphatic aldehydes, quinones, ketones, dicarbonyl compounds and 17-ketosteroids. Catalyzes the NADP(+)-dependent oxidation of aromatic, alicyclic and aliphatic alcohols, and 17beta-hydroxysteroids. To a lesser extent, can also catalyze the reduction of some aldoses and ketoses and the oxidation of some sugar alcohols. In the stomach, lung and colon tissues, mediates the reduction of farnesal and geranylgeranial into farnesol and geranylgeraniol respectivel [...] | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.566 |
Alb | LOC259244-2 | ENSRNOP00000003921 | ENSRNOP00000044277 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.554 |
Apbh | LOC259244-2 | ENSRNOP00000061130 | ENSRNOP00000044277 | Androgen-binding protein eta. | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.663 |
Cyp2a1 | Cyp2c12 | ENSRNOP00000028249 | ENSRNOP00000015802 | Cytochrome P450 2A2; Highly active in the 15-alpha-hydroxylation of testosterone. | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | 0.470 |
Cyp2a1 | Cyp2c13 | ENSRNOP00000028249 | ENSRNOP00000067531 | Cytochrome P450 2A2; Highly active in the 15-alpha-hydroxylation of testosterone. | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.447 |
Cyp2a1 | LOC259244-2 | ENSRNOP00000028249 | ENSRNOP00000044277 | Cytochrome P450 2A2; Highly active in the 15-alpha-hydroxylation of testosterone. | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.523 |
Cyp2c12 | Akr1c15 | ENSRNOP00000015802 | ENSRNOP00000055113 | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | Aldo-keto reductase family 1 member C15; Catalyzes the NADPH-dependent reduction of a variety of substrates including aromatic and aliphatic aldehydes, quinones, ketones, dicarbonyl compounds and 17-ketosteroids. Catalyzes the NADP(+)-dependent oxidation of aromatic, alicyclic and aliphatic alcohols, and 17beta-hydroxysteroids. To a lesser extent, can also catalyze the reduction of some aldoses and ketoses and the oxidation of some sugar alcohols. In the stomach, lung and colon tissues, mediates the reduction of farnesal and geranylgeranial into farnesol and geranylgeraniol respectivel [...] | 0.660 |
Cyp2c12 | Cyp2a1 | ENSRNOP00000015802 | ENSRNOP00000028249 | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | Cytochrome P450 2A2; Highly active in the 15-alpha-hydroxylation of testosterone. | 0.470 |
Cyp2c12 | Cyp2c13 | ENSRNOP00000015802 | ENSRNOP00000067531 | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.823 |
Cyp2c12 | Dhrs7l1 | ENSRNOP00000015802 | ENSRNOP00000036519 | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | Dehydrogenase/reductase (SDR family) member 7-like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.455 |
Cyp2c12 | LOC259244-2 | ENSRNOP00000015802 | ENSRNOP00000044277 | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.565 |
Cyp2c12 | Sult2a1 | ENSRNOP00000015802 | ENSRNOP00000071849 | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | Alcohol sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze sulfonation of hydroxysteroids and xenobiotics; Belongs to the sulfotransferase 1 family. | 0.429 |
Cyp2c13 | Akr1c15 | ENSRNOP00000067531 | ENSRNOP00000055113 | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Aldo-keto reductase family 1 member C15; Catalyzes the NADPH-dependent reduction of a variety of substrates including aromatic and aliphatic aldehydes, quinones, ketones, dicarbonyl compounds and 17-ketosteroids. Catalyzes the NADP(+)-dependent oxidation of aromatic, alicyclic and aliphatic alcohols, and 17beta-hydroxysteroids. To a lesser extent, can also catalyze the reduction of some aldoses and ketoses and the oxidation of some sugar alcohols. In the stomach, lung and colon tissues, mediates the reduction of farnesal and geranylgeranial into farnesol and geranylgeraniol respectivel [...] | 0.656 |
Cyp2c13 | Cyp2a1 | ENSRNOP00000067531 | ENSRNOP00000028249 | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 2A2; Highly active in the 15-alpha-hydroxylation of testosterone. | 0.447 |
Cyp2c13 | Cyp2c12 | ENSRNOP00000067531 | ENSRNOP00000015802 | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | 0.823 |
Cyp2c13 | LOC259244-2 | ENSRNOP00000067531 | ENSRNOP00000044277 | Cytochrome P450 2C13, male-specific; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.586 |
Dhrs7l1 | Cyp2c12 | ENSRNOP00000036519 | ENSRNOP00000015802 | Dehydrogenase/reductase (SDR family) member 7-like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Cytochrome P450 2C12, female-specific; This P450 is active in 15-beta-hydroxylation of steroid sulfates. | 0.455 |
Dhrs7l1 | LOC259244-2 | ENSRNOP00000036519 | ENSRNOP00000044277 | Dehydrogenase/reductase (SDR family) member 7-like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Alpha-2u globulin PGCL3; Belongs to the calycin superfamily. Lipocalin family. | 0.527 |